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Oligodeoxyribonucleotides, Antisense

Known as: Antisense Oligodeoxyribonucleotide, Anti-Sense Oligodeoxyribonucleotides, Oligodeoxyribonucleotide, Antisense 
Short fragments of DNA that are used to alter the function of target RNAs or DNAs to which they hybridize.
National Institutes of Health

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GEM91MG 98OL(1)p53mipomersen
In BloodProcess of secretionagonistsantagonists & inhibitors

Papers overview

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2003
2003
Effect of antisense oligodeoxyribonucleotides targeting at HER-2 mRNA on Caspase-3 protein expression in SK-BR-3 breast cancer cells
AIM To observe the effect of HER-2 specific antisense oligodeoxyribonucleotide HA824 on Caspase-3 protein expression in SK-BR-3… 
2002
2002
1 Cytosolic phospholipase A 2 regulation of human monocyte NADPH oxidase activity : cPLA 2 affects translocation but not phosphorylation of p 67 phox and p 47 phox *
The NADPH oxidase of human monocytes is activated, upon exposure to opsonized zymosan and a variety of other stimuli, to catalyze… 
2001
2001
Antisense Anti-MDM 2 Oligonucleotides As a Novel Therapeutic Approach to Human Breast Cancer : In Vitro and in Vivo Activities and Mechanisms 1
The mouse double minute 2 (MDM2) oncogene has been suggested as a target for cancer therapy. It is amplified or overexpressed in… 
1989
1989
[Synthesis of 5'-phosphorylated oligodeoxyribonucleotides by the H-phosphonate method].
N,O-protected 2'-deoxyribonucleotide-3'-H-phosphonates and 2-(p-nitrophenylethyl)-H-phosphonate were prepared and used in solid… 
1989
1989
[Sequence specificity modification of double-stranded DNA with an alkylating derivative of oligodeoxyribonucleotide pT(CT)6].
It is shown that in slightly acidic solution (pH approximately 5.3) reagent CIRCH2NHpT(CT)6 (RCl = -C6H4-N(CH3)CH2CH2Cl) modifies… 
1989
1989
Two-Dimensional 1 H and 31 P NMR Spectra of a Decamer Oligodeoxyribonucleotide Duplex and a Quinoxaline ((MeCys 3 , MeCys 7 )TANDEM)
1987
1987
The synthesis of protected 5'-mercapto-2',5'-dideoxyribonucleoside-3'-O-phosphoramidites; uses of 5'-mercapto-oligodeoxyribonucleotides.
The syntheses of the four novel, base protected 5'-(S-triphenylmethyl)mercapto-2',5'-dideoxyribonucleoside-3 '-O-(2-cyanoethyl N… 
1984
1984
[DNA-like duplexes containing repetitive sequences. VII. Chemico-enzymatic synthesis of polymers with fragments of natural promotors].
Two types of DNA-duplexes containing the repeating fragments of natural promoters have been obtained starting from synthetic… 
1980
1980
A novel class of condensing reagents in phosphodiester oligodeoxyribonucleotides synthesis. Application of the constituents of free terminal carboxy oxytocine gene.
Benzotriazol-1-yl-oxy-tris (dimethylamino) phosphonium salts have been used as novel condensing agents to promote internucleotide… 
1975
1975
Role of apurinic sites in the resistance of methylated oligodeoxyribonucleotides to degradation by spleen exonuclease.
The effect of introducing methyl groups into DNA substrates was studied by using the spleen exonuclease (EC 3.1.4.1), an enzyme…