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nafadotride

Known as: N-((n-butyl-2-pyrrolidinyl)methyl)-1-methoxy-4-cyanonaphthalene-2-carboxamide 
 
National Institutes of Health

Papers overview

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2014
2014
  • X. Liu, Y. Hou, +5 authors T. Li
  • CNS neuroscience & therapeutics
  • 2014
  • Corpus ID: 27200283
Dopamine and glutamate receptors are densely expressed in the nucleus accumbens (NAc). Active interactions between these… Expand
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2011
2011
Restless legs syndrome (RLS) is a common neurological disorder whose exact pathophysiological mechanism remains unclear despite… Expand
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Highly Cited
2009
Highly Cited
2009
Psychopharmacological studies have implicated the mesolimbic dopamine (DA) system in the mediation of cost/benefit evaluations… Expand
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Highly Cited
2008
Highly Cited
2008
RationaleDopamine is strongly implicated in the ability to shift behavior in response to changing stimulus-reward contingencies… Expand
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Highly Cited
2001
Highly Cited
2001
The conditioning of cocaine's pharmacological actions with environmental stimuli is thought to be a critical factor in long… Expand
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2000
2000
Behavioral sensitization is a well-studied model of behavioral plasticity mediated at least in part by dopaminergic systems… Expand
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Highly Cited
1998
Highly Cited
1998
The benzofurane (+)-S 14297, the benzamide nafadotride, the aminoindane U 99194 and the arylpiperazine GR 103,691 have been… Expand
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Highly Cited
1997
Highly Cited
1997
In rats with unilateral lesions of the nigrostriatal dopamine pathway with 6-hydroxydopamine, the motor stimulating effects of… Expand
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1997
1997
Nafadotride has been proposed as a selective antagonist for the D3 dopamine receptor. This drug has been shown to exhibit… Expand
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Highly Cited
1995
Highly Cited
1995
Nafadotride (N[(n-butyl-2-pyrrolidinyl)methyl]-1-methoxy-4-cyano naphtalene-2-carboxamide) is a novel compound, which inhibits… Expand
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