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nafadotride

Known as: N-((n-butyl-2-pyrrolidinyl)methyl)-1-methoxy-4-cyanonaphthalene-2-carboxamide 
National Institutes of Health

Papers overview

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2014
2014
Dopamine and glutamate receptors are densely expressed in the nucleus accumbens (NAc). Active interactions between these… Expand
Highly Cited
2009
Highly Cited
2009
Psychopharmacological studies have implicated the mesolimbic dopamine (DA) system in the mediation of cost/benefit evaluations… Expand
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Highly Cited
2008
Highly Cited
2008
RationaleDopamine is strongly implicated in the ability to shift behavior in response to changing stimulus-reward contingencies… Expand
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2007
2007
Dopamine D3 receptor partial agonism has been suggested as a potential therapeutic intervention in cocaine addiction. RGH-237 [N… Expand
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Highly Cited
2001
Highly Cited
2001
The conditioning of cocaine's pharmacological actions with environmental stimuli is thought to be a critical factor in long… Expand
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Highly Cited
1998
Highly Cited
1998
The benzofurane (+)-S 14297, the benzamide nafadotride, the aminoindane U 99194 and the arylpiperazine GR 103,691 have been… Expand
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Highly Cited
1997
Highly Cited
1997
In rats with unilateral lesions of the nigrostriatal dopamine pathway with 6-hydroxydopamine, the motor stimulating effects of… Expand
1997
1997
Nafadotride has been proposed as a selective antagonist for the D3 dopamine receptor. This drug has been shown to exhibit… Expand
Highly Cited
1997
Highly Cited
1997
The three dopamine agonists with highest reported D3 receptor selectivity in vitro, pramipexole, quinelorane and PD128,907… Expand
Highly Cited
1995
Highly Cited
1995
Nafadotride (N[(n-butyl-2-pyrrolidinyl)methyl]-1-methoxy-4-cyano naphtalene-2-carboxamide) is a novel compound, which inhibits… Expand