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Role of 5-hydroxytryptamine1B receptors and 5-hydroxytryptamine uptake inhibition in the cocaine-evoked discriminative stimulus effects in rats.
Mesolimbic dopamine pathways play a critical role in the behavioural effects of cocaine in rodents. Nonetheless, research has also demonstrated involvement of 5-hydroxytryptamine (5-HT; serotonin)Expand
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Effects of CP 154,526, a CRF1 receptor antagonist, on behavioral responses to cocaine in rats
We examined the influence of CP 154,526, a selective antagonist of corticotropin-releasing factor (CRF)1 receptors, in the locomotor, sensitizing, discriminative stimulus and rewarding effects ofExpand
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Effects of 5-HT1B receptor ligands microinjected into the accumbal shell or core on the cocaine-induced locomotor hyperactivity in rats.
The present study was designed to examine the effect of 5-HT1B receptor ligands microinjected into the subregions of the nucleus accumbens (the shell and the core) on the locomotor hyperactivityExpand
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Effects of 5-HT1B receptor ligands microinjected into the ventral tegmental area on the locomotor and sensitizating effects of cocaine in rats
The present study was aimed at finding out whether 5-HT(1B) receptors located in the ventral tegmental area (VTA) played a role in the locomotor hyperactivity induced by a single dose of cocaine andExpand
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Effects of 5-HT1B receptor ligands microinjected into the ventral tegmental area on cocaine discrimination in rats.
Some recent data indicate a significant interaction between serotonin (5-hydroxytryptamine; 5-HT) and dopamine in mesolimbic brain structures (e.g. the ventral tegmental area) which modulate theExpand
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Role of dopamine D3 receptors in controlling the expression of cocaine sensitization in rats.
It is established that dopamine (DA) is an important brain mediator of the behavioral (i.e. sensitizing) effects of cocaine in rodents. Among DA receptors, recent findings point to engagement of DAExpand
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Effect of serotonin (5-HT)1B receptor ligands on cocaine sensitization in rats.
Recent studies have shown that antagonists of serotonin (5-HT)1B receptors attenuate cocaine-induced locomotor hyperactivity, whereas agonists enhance reinforcing and discriminative stimulus effectsExpand
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Role of 5-HT(1B) receptors in the sensitization to amphetamine in mice.
The present study was designed to determine how 5-HT(1B) receptor ligands affected the development or the expression phase of sensitization to the amphetamine-induced locomotor response in mice. MiceExpand
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On the role of serotonin2A/2C receptors in the sensitization to cocaine.
Apart from showing involvement of dopamine, recent studies also indicate a role of serotonin (5-HT) in the behavioral effects of cocaine in rodents. In the present study we investigated the role ofExpand
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Effects of serotonin (5-HT)1B receptor ligands, microinjected into accumbens subregions, on cocaine discrimination in rats
Abstract. Recent data indicate a significant input of serotonin (5-HT) on mesoaccumbens dopamine-dependent behavioral effects of cocaine in rats. The present study investigated the role of 5-HT1BExpand
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