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motexafin gadolinium
Known as:
Gd (III) Texaphryin
, Gadolinium Texaphyrin
, Gd(III) texaphyrin
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A synthetic metallotexaphyrin with radiosensitizing and chemosensitizing properties. Motexafin gadolinium accumulates in tumor cells preferentially…
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National Institutes of Health
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Related topics
Related topics
10 relations
Broader (4)
Antineoplastic Agents
Contrast Media
Metalloporphyrins
Photosensitizing Agents
DNA Breaks, Double-Stranded
Free Radical Formation
Positive Regulation of Apoptosis
chemosensitization/potentiation
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Narrower (1)
Xcytrin
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Clinical development of photodynamic agents and therapeutic applications
R. Baskaran
,
Junghan Lee
,
Su-Geun Yang
Biomaterials Research
2018
Corpus ID: 52898820
BackgroundPhotodynamic therapy (PDT) is photo-treatment of malignant or benign diseases using photosensitizing agents, light, and…
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Review
2012
Review
2012
Treatment of brain metastases: review of phase III randomized controlled trials.
S. Scoccianti
,
U. Ricardi
Radiotherapy and Oncology
2012
Corpus ID: 21878850
Review
2010
Review
2010
Macromolecules, dendrimers, and nanomaterials in magnetic resonance imaging: the interplay between size, function, and pharmacokinetics.
A. J. L. Villaraza
,
A. Bumb
,
M. Brechbiel
Chemical Reviews
2010
Corpus ID: 13783529
Magnetism in medicine has had a long and interesting history. In the 10 th century A.D., Egyptian physician and philosopher…
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Highly Cited
2006
Highly Cited
2006
Motexafin Gadolinium, a Tumor-selective Drug Targeting Thioredoxin Reductase and Ribonucleotide Reductase*
S. Hashemy
,
J. Ungerstedt
,
F. Z. Avval
,
A. Holmgren
Journal of Biological Chemistry
2006
Corpus ID: 33680469
Motexafin gadolinium (MGd) is a chemotherapeutic drug that selectively targets tumor cells and mediates redox reactions…
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Review
2004
Review
2004
Neurocognitive function and progression in patients with brain metastases treated with whole-brain radiation and motexafin gadolinium: results of a randomized phase III trial.
C. Meyers
,
Jennifer A. Smith
,
+14 authors
M. Renschler
Journal of Clinical Oncology
2004
Corpus ID: 33974996
PURPOSE To report the neurocognitive findings in a phase III randomized trial evaluating survival and neurologic and…
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Review
2004
Review
2004
The emerging role of reactive oxygen species in cancer therapy.
M. Renschler
European Journal of Cancer
2004
Corpus ID: 13587006
Review
2003
Review
2003
Survival and neurologic outcomes in a randomized trial of motexafin gadolinium and whole-brain radiation therapy in brain metastases.
M. Mehta
,
P. Rodrigus
,
+14 authors
M. Renschler
Journal of Clinical Oncology
2003
Corpus ID: 24980336
PURPOSE This phase III randomized trial evaluated survival as well as neurologic and neurocognitive function in patients with…
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Highly Cited
1999
Highly Cited
1999
In vivo animal studies with gadolinium (III) texaphyrin as a radiation enhancer.
R. Miller
,
K. Woodburn
,
Q. Fan
,
M. Renschler
,
J. Sessler
,
J. Koutcher
International Journal of Radiation Oncology…
1999
Corpus ID: 37618014
Highly Cited
1996
Highly Cited
1996
Gadolinium(III) texaphyrin: a tumor selective radiation sensitizer that is detectable by MRI.
S. Young
,
F. Qing
,
+6 authors
R. Miller
Proceedings of the National Academy of Sciences…
1996
Corpus ID: 12119088
Gadolinium(III) texaphyrin (Gd-tex2+) is representative of a new class of radiation sensitizers detectable by magnetic resonance…
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Highly Cited
1996
Highly Cited
1996
Lutetium Texaphyrin (PCI‐0123): A Near‐Infrared, Water‐Soluble Photosensitizer
S. W. Young
,
K. Woodburn
,
+5 authors
R. Miller
Photochemistry and Photobiology
1996
Corpus ID: 31732810
Lutetium texaphyrin, PCI‐0123, is a pure, water‐soluble photosensitizer with a large broad absorption band centered at 732 nm…
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