DNA Breaks, Double-Stranded

Known as: DNA Breaks, Double Stranded, Break, Double-Stranded DNA, Break, Double-Strand DNA 
A DNA Double Strand Break involves a disruption of the covalent linkages among the phosphodeoxyribose moieties within the sugar-phosphate backbone in… (More)

Topic mentions per year

Topic mentions per year

1992-2018
051019922018

Papers overview

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2016
2016
Repetitive DNA is packaged into heterochromatin to maintain its integrity. We use CRISPR/Cas9 to induce DSBs in different… (More)
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2015
2015
The Mre11-Rad50-Xrs2 nuclease complex, together with Sae2, initiates the 5'-to-3' resection of Double-Strand DNA Breaks (DSBs… (More)
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2012
2012
A DNA double strand break (DSB) is a highly toxic lesion, which can generate genetic instability and profound genome… (More)
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2012
2012
Homologous recombination (HR) plays an important role in the maintenance of genome integrity. HR repairs broken DNA during S and… (More)
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2011
2011
Regardless of the achievable remissions with first line hormone therapy in patients with prostate cancer (CaP), the disease… (More)
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2010
2010
Ionizing radiation has been proved a major stress that can induce carcinogenesis. Nuclear DNA is the main target of ionizing… (More)
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2010
2010
WRN-1 is the Caenorhabditis elegans homolog of the human Werner syndrome protein, a RecQ helicase, mutations of which are… (More)
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2009
2009
Telomere maintenance is required for chromosome stability, and telomeres are typically replicated by the action of telomerase. In… (More)
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2008
2008
Little information is available on the ability of terminally differentiated cells to efficiently repair DNA double strand breaks… (More)
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2000
2000
Immature CD4(+)CD8(+) thymocytes rearrange their T cell receptor (TCR)-alpha gene locus to generate clonotypic alpha/beta TCR… (More)
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