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Double Strand Break Repair

Known as: Double-Strand Break Repair 
The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix. [GOC:elh]
National Institutes of Health

Related topics

Related topics

50 relations
BABAM1 geneBABAM1 protein, humanBRCA1 geneBRCA1 protein, human

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DNA strand renaturation involved in double-strand break repair

Papers overview

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Highly Cited
2005
Highly Cited
2005
Distinct roles for the RSC and Swi/Snf ATP-dependent chromatin remodelers in DNA double-strand break repair.
The failure of cells to repair damaged DNA can result in genomic instability and cancer. To efficiently repair chromosomal DNA… 
Review
2004
Review
2004
Mechanisms of DNA double strand break repair and chromosome aberration formation
It is widely accepted that unrepaired or misrepaired DNA double strand breaks (DSBs) lead to the formation of chromosome… 
Review
2004
Review
2004
DNA double-strand break repair by homologous recombination.
Review
2002
Review
2002
Role of RAD52 Epistasis Group Genes in Homologous Recombination and Double-Strand Break Repair
SUMMARY The process of homologous recombination is a major DNA repair pathway that operates on DNA double-strand breaks, and… 
Highly Cited
2002
Highly Cited
2002
Involvement of human polynucleotide kinase in double‐strand break repair by non‐homologous end joining
The efficient repair of double‐strand breaks (DSBs) in DNA is critical for the maintenance of genome stability. In mammalian… 
Review
1998
Review
1998
Molecular mechanisms of DNA double strand break repair.
Highly Cited
1998
Highly Cited
1998
The hMre11/hRad50 Protein Complex and Nijmegen Breakage Syndrome: Linkage of Double-Strand Break Repair to the Cellular DNA Damage Response
Highly Cited
1998
Highly Cited
1998
Capture of genomic and T‐DNA sequences during double‐strand break repair in somatic plant cells
To analyze genomic changes resulting from double‐strand break (DSB) repair, transgenic tobacco plants were obtained that carried… 
Highly Cited
1998
Highly Cited
1998
In situ visualization of DNA double-strand break repair in human fibroblasts.
A method was developed to examine DNA repair within the intact cell. Ultrasoft x-rays were used to induce DNA double-strand… 
Highly Cited
1996
Highly Cited
1996
Genetic requirements for the single-strand annealing pathway of double-strand break repair in Saccharomyces cerevisiae.
HO endonuclease-induced double-strand breaks (DSBs) within a direct duplication of Escherichia coli lacZ genes are repaired… 
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