Skip to search formSkip to main contentSkip to account menu

Double Strand Break Repair

Known as: Double-Strand Break Repair 
The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix. [GOC:elh]
National Institutes of Health

Related topics

Related topics

50 relations
BABAM1 geneBABAM1 protein, humanBRCA1 geneBRCA1 protein, human

Narrower (1)

DNA strand renaturation involved in double-strand break repair

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Long-term XPC silencing reduces DNA double-strand break repair.
To study the relationships between different DNA repair pathways, we established a set of clones in which one specific DNA repair… 
Highly Cited
2001
Highly Cited
2001
Alterations of the double-strand break repair gene MRE11 in cancer.
MRE11 plays a role in DNA double-strand break repair. Hypomorphic mutations of MRE11 have been demonstrated in ataxia… 
Review
2000
Review
2000
The Sir proteins of Saccharomyces cerevisiae: mediators of transcriptional silencing and much more.
Highly Cited
2000
Highly Cited
2000
The Saccharomyces cerevisiae Msh2 mismatch repair protein localizes to recombination intermediates in vivo.
Highly Cited
1996
Highly Cited
1996
Wortmannin is a potent inhibitor of DNA double strand break but not single strand break repair in Chinese hamster ovary cells.
Wortmannin, an inhibitor of p110 PI 3-kinase, also inhibits DNA-dependent protein kinase, which is known to mediate DNA double… 
Highly Cited
1996
Highly Cited
1996
Involvement of the Saccharomyces cerevisiae HDF1 Gene in DNA Double-strand Break Repair and Recombination (*)
The HDF1 protein of Saccharomyces cerevisiae shares biochemical properties and structural homology with the 70-kDa subunit of the… 
Highly Cited
1990
Highly Cited
1990
DNA double-strand break repair pathways and cellular tolerance to inhibitors of topoisomerase II.
The Chinese hamster ovary cell line xrs-1 is hypersensitive to gamma-radiation. This sensitivity has been attributed to an… 
1990
1990
Effects of hyperthermia on the repair of radiation-induced DNA single- and double-strand breaks in DNA double-strand break repair-deficient and repair-proficient cell lines.
The effect of heat on the induction and repair of DNA single (ssb) and double (dsb) strand breaks was studied in irradiated… 
Highly Cited
1980
Highly Cited
1980
Repair of DNA double-strand breaks in irradiated yeast cells under nongrowth conditions.
We show that in diploid yeast radiation-induced DNA double-strand breaks can be repaired under nongrowth conditions at 30/sup 0/C… 
Highly Cited
1975
Highly Cited
1975
The repair of double-strand breaks in chromosomal DNA of yeast.
Ionizing radiation induces double-strand breaks in the nuclear DNA of the yeast Saccharomyces cerevisiae with an efficiency of… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)