5-chloroquinoxaline-2-sulfanilamide

Known as: Chloroquinoxaline Sulfonamide, Benzenesulfonamide, 4-amino-N-[5-chloro-2-quinoxalinyl]-, Benzenesulfonamide, 4-amino-N-(5-chloro-2-quinoxalinyl)- 
A chlorinated heterocyclic sulfanilamide with potential antineoplastic activity and potential immunosuppressive activity. Chloroquinoxaline… (More)
National Institutes of Health

Related topics

Related topics

8 relations
DNA Breaks, Double-StrandedDNA Repair InhibitionDNA topoisomerase II alphaNatural immunosuppression
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Broader (2)

QuinoxalinesSulfanilamides

Papers overview

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2014
2014
Metabolic QTL Analysis Links Chloroquine Resistance in Plasmodium falciparum to Impaired Hemoglobin Catabolism
Drug resistant strains of the malaria parasite, Plasmodium falciparum, have rendered chloroquine ineffective throughout much of… (More)
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2006
2006
Spinning disk confocal microscopy of live, intraerythrocytic malarial parasites. 2. Altered vacuolar volume regulation in drug resistant malaria.
In the previous paper [Gligorijevic, B., et al. (2006) Biochemistry 45, pp 12400-12410], we reported on a customized Nipkow… (More)
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2006
2006
PfCRT and the trans-vacuolar proton electrochemical gradient: regulating the access of chloroquine to ferriprotoporphyrin IX.
It is accepted that resistance of Plasmodium falciparum to chloroquine (CQ) is caused primarily by mutations in the pfcrt gene… (More)
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2004
2004
Drug resistance-associated pfCRT mutations confer decreased Plasmodium falciparum digestive vacuolar pH.
Elucidating the altered physiology of various chloroquine resistant (CQR) strains of Plasmodium falciparum is essential for… (More)
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2003
2003
Causes of phytotoxicity of metsulfuron-methyl bound residues in soil.
The bioavailability and phytotoxicity of bound residues of metsulfuron-methyl were studied using 14C-labeling and bioassay with… (More)
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Highly Cited
1998
Highly Cited
1998
Laryngeal adduction in resonant voice.
The primary question in this study was whether subjects with nodules and subjects with healthy larynges would produce "resonant… (More)
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Highly Cited
1998
Highly Cited
1998
Role for the plasmodium falciparum digestive vacuole in chloroquine resistance.
We have developed a method for the isolation of pure and intact Plasmodium falciparum digestive vacuoles capable of ATP-dependent… (More)
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1998
1998
Differential Stimulation of the Na+/H+ Exchanger Determines Chloroquine Uptake in Plasmodium falciparum
Here we describe the identification and characterization of a physiological marker that is associated with the chloroquine… (More)
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Highly Cited
1990
Highly Cited
1990
Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum
THE lethal form of human malaria caused by Plasmodium falciparum is virtually uncontrollable in many areas because of the… (More)
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Highly Cited
1990
Highly Cited
1990
Chloroquine resistance not linked to mdr-like genes in a Plasmodium falciparum cross
CHLOROQUINE is thought to act against falciparum malaria by accumulating in the acid vesicles of the parasite and interfering… (More)
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