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monoclonal antibody A27.15
Known as:
A27.15
, ANTI-TRANSFERRIN MOAB 27.15
, MOAB A27.15
A murine IgG1 monoclonal antibody directed against the human transferrin (Tf) receptor. Monoclonal antibody A27.15 binds to the Tf receptor, blocking…
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National Institutes of Health
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Related topics
Related topics
5 relations
Inhibition of Cell Proliferation
Negative Regulation of Receptor Activation
Transferrin Receptor
antigen binding
Broader (1)
Monoclonal Antibodies
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Effects of transferrin receptor blockade on cancer cell proliferation and hypoxia-inducible factor function and their differential regulation by ascorbate.
Dylan T. Jones
,
I. Trowbridge
,
A. Harris
Cancer research
2006
Corpus ID: 25226325
Cellular iron is needed for cell survival and hydroxylation of hypoxia-inducible factor-1alpha (HIF-alpha) by prolyl hydroxylases…
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1996
1996
alpha-Interferon potentiates the growth inhibitory effects of anti-transferrin receptor monoclonal antibodies.
M. Caraglia
,
A. Leardi
,
+6 authors
P. Tagliaferri
International journal of oncology
1996
Corpus ID: 5707501
We have demonstrated that interferon-alpha 2 recombinant (IFN alpha) inhibits the growth and modulates the expression of the…
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1995
1995
Differing sensitivity of non-hematopoietic human tumors to synergistic anti-transferrin receptor monoclonal antibodies and deferoxamine in vitro.
J. Kovar
,
P. Naumann
,
B. C. Stewart
,
J. Kemp
Pathobiology : journal of immunopathology…
1995
Corpus ID: 46868018
We tested non-hematopoietic human tumors for in vitro sensitivity to either a pair of synergistic IgG antitransferrin (Tf…
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1994
1994
Effects of combined antigrowth factor receptor treatment on in vitro growth of multiple myeloma.
R. Taetle
,
B. Dos Santos
,
+4 authors
W. Dalton
Journal of the National Cancer Institute
1994
Corpus ID: 24759113
BACKGROUND Although passive serotherapy for cancer with monoclonal antibodies is an attractive concept, it has unfortunately had…
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Highly Cited
1990
Highly Cited
1990
Combinations of anti-transferrin receptor monoclonal antibodies inhibit human tumor cell growth in vitro and in vivo: evidence for synergistic antiproliferative effects.
S. White
,
R. Taetle
,
P. Seligman
,
M. Rutherford
,
I. Trowbridge
Cancer research
1990
Corpus ID: 8073793
Thirty-two murine monoclonal antibodies (MAbs) against the external domain of the human transferrin (Tf) receptor have been…
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