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monoclonal antibody A27.15

Known as: A27.15, ANTI-TRANSFERRIN MOAB 27.15, MOAB A27.15 
A murine IgG1 monoclonal antibody directed against the human transferrin (Tf) receptor. Monoclonal antibody A27.15 binds to the Tf receptor, blocking… Expand
National Institutes of Health

Related topics

Related topics

5 relations
Inhibition of Cell ProliferationNegative Regulation of Receptor ActivationTransferrin Receptorantigen binding

Broader (1)

Monoclonal Antibodies

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Effects of transferrin receptor blockade on cancer cell proliferation and hypoxia-inducible factor function and their differential regulation by ascorbate.
Cellular iron is needed for cell survival and hydroxylation of hypoxia-inducible factor-1alpha (HIF-alpha) by prolyl hydroxylases… Expand
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1996
1996
alpha-Interferon potentiates the growth inhibitory effects of anti-transferrin receptor monoclonal antibodies.
We have demonstrated that interferon-alpha 2 recombinant (IFN alpha) inhibits the growth and modulates the expression of the… Expand
1995
1995
Differing sensitivity of non-hematopoietic human tumors to synergistic anti-transferrin receptor monoclonal antibodies and deferoxamine in vitro.
We tested non-hematopoietic human tumors for in vitro sensitivity to either a pair of synergistic IgG antitransferrin (Tf… Expand
1994
1994
Effects of combined antigrowth factor receptor treatment on in vitro growth of multiple myeloma.
BACKGROUND Although passive serotherapy for cancer with monoclonal antibodies is an attractive concept, it has unfortunately had… Expand
Highly Cited
1990
Highly Cited
1990
Combinations of anti-transferrin receptor monoclonal antibodies inhibit human tumor cell growth in vitro and in vivo: evidence for synergistic antiproliferative effects.
Thirty-two murine monoclonal antibodies (MAbs) against the external domain of the human transferrin (Tf) receptor have been… Expand
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