Effects of combined antigrowth factor receptor treatment on in vitro growth of multiple myeloma.

@article{Taetle1994EffectsOC,
  title={Effects of combined antigrowth factor receptor treatment on in vitro growth of multiple myeloma.},
  author={Raymond Taetle and B Dos Santos and Yoshiyuki Ohsugi and Yasuo Gotenba-shi Koishihara and Y. Yamada and Hans A. Messner and W Dalton},
  journal={Journal of the National Cancer Institute},
  year={1994},
  volume={86 6},
  pages={
          450-5
        }
}
BACKGROUND Although passive serotherapy for cancer with monoclonal antibodies is an attractive concept, it has unfortunately had limited efficacy in clinical trials. An alternative approach to passive serotherapy is targeting cell surface growth factor receptors with monoclonal antibodies. With some limitations, anti-growth factor receptor antibodies can limit cell growth by blocking stimulatory or trophic growth factor receptors and by marshaling in vivo antitumor immune responses. PURPOSE… Expand
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