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methyl-(4-carboxyphenyl)glycine

Known as: MCPG cpd 
National Institutes of Health

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2 relations

Broader (1)

Glycine
analogs & derivatives

Papers overview

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Highly Cited
2002
Highly Cited
2002
Dendritic spines elongate after stimulation of group 1 metabotropic glutamate receptors in cultured hippocampal neurons
Changes in the morphology of dendritic spines are correlated with synaptic plasticity and may relate mechanistically to its… 
Highly Cited
1999
Highly Cited
1999
Activation of the extracellular signal‐regulated kinase 2 by metabotropic glutamate receptors
Activation of metabotropic glutamate receptors (mGluRs) leads to modulation of a variety of second messenger pathways probably… 
Highly Cited
1997
Highly Cited
1997
Group 1 and 2 Metabotropic Glutamate Receptors Play Differential Roles in Hippocampal Long-Term Depression and Long-Term Potentiation in Freely Moving Rats
This study examined the role of metabotropic glutamate receptors (mGluRs) in hippocampal long-term depression (LTD) in vivo. The… 
Highly Cited
1997
Highly Cited
1997
LY354740 is a Potent and Highly Selective Group II Metabotropic Glutamate Receptor Agonist in Cells Expressing Human Glutamate Receptors
Highly Cited
1995
Highly Cited
1995
Phenylglycine derivatives discriminate between mGluR1- and mGluR5-mediated responses
Highly Cited
1995
Highly Cited
1995
Metabotropic glutamate receptor-mediated presynaptic depression at corticostriatal synapses involves mGLuR2 or 3.
1. The pharmacology of the metabotropic glutamate receptor (mGluR) that mediates synaptic depression at corticostriatal synapses… 
Highly Cited
1995
Highly Cited
1995
Metabotropic glutamate receptor-induced homosynaptic long-term depression and depotentiation in the dentate gyrus of the rat hippocampus in vitro
Highly Cited
1995
Highly Cited
1995
Reexamination of the effects of MCPG on hippocampal LTP, LTD, and depotentiation.
1. We examined the effects of the metabotropic glutamate receptor (mGluR) antagonist alpha-methyl-4-carboxyphenylglycine (MCPG… 
Highly Cited
1994
Highly Cited
1994
MCPG Antagonizes Metabotropic Glutamate Receptors but not Long‐term Potentiation in the Hippocampus
In the CA1 and CA3 regions of the guinea pig hippocampus, we have tested the ability of the new antagonist (RS)‐α‐methyl‐4… 
Highly Cited
1994
Highly Cited
1994
Actions of two new antagonists showing selectivity for different sub‐types of metabotropic glutamate receptor in the neonatal rat spinal cord
1 The presynaptic depressant action of l‐2‐amino‐4‐phosphonobutyrate (l‐AP4) on the monosynaptic excitation of neonatal rat… 
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