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meropenem
Known as:
1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 3-((5-((dimethylamino)carbonyl)-3-pyrrolidinyl)thio)-6-(1-hydroxyethyl)-4-methyl-7-oxo-, (4R-(3(3S*,5S*),4alpha,5beta,6beta(R*)))-
, meropenem [Chemical/Ingredient]
, 3-(5-dimethylcarbamoylpyrrolidin-3-ylthio)-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid
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A broad-spectrum carbapenem with antibacterial properties, synthetic Meropenem inhibits cell wall synthesis in gram-positive and gram-negative…
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National Institutes of Health
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Related topics
Related topics
30 relations
Broader (2)
Anti-Bacterial Agents
Thienamycins
Appendicitis
Bacterial Infections
Bacteroides Infections
Carbapenems
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Narrower (6)
Meropenem Hydrate
Meropenem trihydrate
Merrem
Penem
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
In vitro activity of ceftazidime, ciprofloxacin, meropenem, minocycline, tobramycin and trimethoprim/sulfamethoxazole against planktonic and sessile Burkholderia cepacia complex bacteria.
E. Peeters
,
H. Nelis
,
T. Coenye
Journal of Antimicrobial Chemotherapy
2009
Corpus ID: 33061452
OBJECTIVES The goal of the present study was to obtain a comprehensive overview of the bacteriostatic and bactericidal effects of…
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2008
2008
Association between antibiotic usage and subsequent colonization or infection of extensive drug-resistant Acinetobacter baumannii: a matched case-control study in intensive care units.
H. Tsai
,
Jann-Tay Wang
,
Chien-Jen Chen
,
Shan-Chwen Chang
Diagnostic microbiology and infectious disease
2008
Corpus ID: 25538058
Highly Cited
2007
Highly Cited
2007
Prevalence, mechanisms, and risk factors of carbapenem resistance in bloodstream isolates of Pseudomonas aeruginosa.
V. Tam
,
Kai-tai Chang
,
+4 authors
K. Garey
Diagnostic microbiology and infectious disease
2007
Corpus ID: 25383894
Highly Cited
2005
Highly Cited
2005
Pharmacodynamic Evaluation of Extending the Administration Time of Meropenem using a Monte Carlo Simulation
B. Lomaestro
,
G. Drusano
Antimicrobial Agents and Chemotherapy
2005
Corpus ID: 23642413
ABSTRACT A Monte Carlo simulation demonstrated that 1 g of meropenem (MEM) every 8 h (q8h) (3-h infusion) has a higher target…
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2005
2005
Class 2 Integron with a Novel Cassette Array in a Burkholderia cenocepacia Isolate
M. Ramírez
,
L. Vargas
,
Viviana Cagnoni
,
M. Tokumoto
,
D. Centrón
Antimicrobial Agents and Chemotherapy
2005
Corpus ID: 40568514
Burkholderia cepacia complex (BCC) organisms are gram-negative opportunistic emerging pathogens associated with a poor prognosis…
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Highly Cited
2003
Highly Cited
2003
Sustained activity and spectrum of selected extended-spectrum beta-lactams (carbapenems and cefepime) against Enterobacter spp. and ESBL-producing Klebsiella spp.: report from the SENTRY…
Ronald N. Jones
,
D. Biedenbach
,
A. Gales
International Journal of Antimicrobial Agents
2003
Corpus ID: 22168747
Highly Cited
2001
Highly Cited
2001
MYSTIC program: summary of European data from 1997 to 2000.
H. Goossens
Diagnostic microbiology and infectious disease
2001
Corpus ID: 37136303
Review
2000
Review
2000
Cephalosporins, carbapenems, and monobactams.
L. Asbel
,
M. Levison
Infectious Disease Clinics of North America
2000
Corpus ID: 13797037
Review
2000
Review
2000
MYSTIC (Meropenem Yearly Susceptibility Test Information Collection): a global overview.
P. Turner
Journal of Antimicrobial Chemotherapy
2000
Corpus ID: 10837006
The Meropenem Yearly Susceptibility Test Information Collection (MYSTIC) is a global, multicentre surveillance study that…
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Highly Cited
2000
Highly Cited
2000
Elimination of meropenem during continuous veno-venous haemofiltration and haemodiafiltration in patients with acute renal failure.
M. Valtonen
,
E. Tiula
,
J. Backman
,
P. Neuvonen
Journal of Antimicrobial Chemotherapy
2000
Corpus ID: 18019770
Meropenem elimination was studied in six patients with acute renal failure on continuous venovenous haemofiltration (CVVH) or…
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