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meropenem

Known as: 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 3-((5-((dimethylamino)carbonyl)-3-pyrrolidinyl)thio)-6-(1-hydroxyethyl)-4-methyl-7-oxo-, (4R-(3(3S*,5S*),4alpha,5beta,6beta(R*)))-, meropenem [Chemical/Ingredient], 3-(5-dimethylcarbamoylpyrrolidin-3-ylthio)-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid 
A broad-spectrum carbapenem with antibacterial properties, synthetic Meropenem inhibits cell wall synthesis in gram-positive and gram-negative… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Carbapenems are considered as last-resort antibiotics for the treatment of infections caused by multidrug-resistant Gram-negative… Expand
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Highly Cited
2009
Highly Cited
2009
β-lactam antibiotics are ineffective against Mycobacterium tuberculosis, being rapidly hydrolyzed by the chromosomally encoded… Expand
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Review
2009
Review
2009
From early this decade, Enterobacteriaceae that produce Klebsiella pneumoniae carbapenemases (KPC) were reported in the USA and… Expand
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Review
2002
Review
2002
Carbapenemases may be defined as beta-lactamases that significantly hydrolyze at least imipenem or/and meropenem. Carbapenemases… Expand
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Highly Cited
2001
Highly Cited
2001
ABSTRACT A Klebsiella pneumoniae isolate showing moderate to high-level imipenem and meropenem resistance was investigated. The… Expand
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Review
2001
Review
2001
  • K. Poole
  • Journal of molecular microbiology and…
  • 2001
  • Corpus ID: 1463235
Pseudomonas aeruginosa is an opportunistic human pathogen characterized by an innate resistance to multiple antimicrobial agents… Expand
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Highly Cited
2000
Highly Cited
2000
BACKGROUND The emergence of drug-resistant strains of bacteria has complicated treatment decisions and may lead to treatment… Expand
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Highly Cited
1999
Highly Cited
1999
Abstract. Most antibiotics are metabolized only incompletely by patients after administration and enter the municipal sewage with… Expand
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Highly Cited
1992
Highly Cited
1992
Multiple-drug-resistant mutants were isolated from Pseudomonas aeruginosa PAO1 on agar plates containing ofloxacin and cefsulodin… Expand
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Highly Cited
1991
Highly Cited
1991
Infection is a leading cause of mortality and morbidity in the newborn. The smaller and more preterm the baby, the higher the… Expand
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