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Thienamycins

Known as: Antibiotics, Thienamycin, Thienamycin Antibiotics, Thienamycins [Chemical/Ingredient] 
Beta-lactam antibiotics that differ from PENICILLINS in having the thiazolidine sulfur atom replaced by carbon, the sulfur then becoming the first… Expand
National Institutes of Health

Papers overview

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Highly Cited
1985
Highly Cited
1985
Radioactive- and stable isotope-containing substrates were used to identify the biosynthetic precursors of the beta-lactam… Expand
Highly Cited
1983
Highly Cited
1983
N-Formimidoyl thienamycin (MK0787) undergoes renal metabolism by a dipeptidase, dehydropeptidase I, located on the brush border… Expand
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Highly Cited
1983
Highly Cited
1983
The pharmacokinetics of intravenously administered N-formimidoyl thienamycin (MK0787) were studied in 14 healthy male subjects in… Expand
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Highly Cited
1982
Highly Cited
1982
Thienamycin (THM), the N-formimidoyl thienamycin derivative MK0787, and related carbapenem antibiotics were metabolized… Expand
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Highly Cited
1982
Highly Cited
1982
The in vitro activity of N-formimidoyl thienamycin was determined against 800 gram-positive and gram-negative aerobic and… Expand
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Highly Cited
1982
Highly Cited
1982
Two types of beta-lactamase were found in the cell-free extract from Pseudomonas maltophilia GN12873. One was an inducible… Expand
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Highly Cited
1981
Highly Cited
1981
The susceptibilities of 12 strains of enterococci and 10 stains of Listeria monocytogenes to N-formimidoyl thienamycin were… Expand
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Highly Cited
1980
Highly Cited
1980
The in vitro activity of a new crystalline derivative of thienamycin, N-formimidoyl thienamycin (MK0787), was tested against 46… Expand
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1980
1980
N-Formimidoyl thienamycin (MK0787) is a derivative of thienamycin, a unique, new beta-lactam antibiotic. Its activity against 285… Expand
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Highly Cited
1980
Highly Cited
1980
The in vitro activity of N-formimidoyl thienamycin (MK0787), a stable congener of thienamycin, was determined against 200 species… Expand
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