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Carbapenems

Known as: Carbapenem Antibiotics, Lenapenem, carbapenem 
A broad-spectrum, carbapenem antibiotic with bactericidal activity. Lenapenem binds to penicillin binding proteins (PBPs) located on the bacterial… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Antibiotic resistance is a global health crisis linked to increased, and often unrestricted, antibiotic use in humans and animals… Expand
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Review
2018
Review
2018
BACKGROUND The spread of antibiotic-resistant bacteria poses a substantial threat to morbidity and mortality worldwide. Due to… Expand
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Review
2018
Review
2018
The Working Party makes more than 100 tabulated recommendations in antimicrobial prescribing for the treatment of infections… Expand
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Review
2018
Review
2018
Klebsiella pneumoniae is a Gram-negative pathogen that has a large accessory genome of plasmids and chromosomal gene loci. This… Expand
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Review
2018
Review
2018
The hospital environment is a potential reservoir of bacteria with plasmids conferring carbapenem resistance. Our Hospital… Expand
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Review
2017
Review
2017
Carbapenem resistance is a major and an on-going public health problem globally. It occurs mainly among Gram-negative pathogens… Expand
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Review
2017
Review
2017
Klebsiella pneumoniae is one of the most clinically relevant species in immunocompromised individuals responsible for community… Expand
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Review
2017
Review
2017
BackgroundInfections with carbapenem-resistant Enterobacteriaceae (CRE) are increasingly being reported from patients in… Expand
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Review
2017
Review
2017
  • Robert A. Bonomo
  • Cold Spring Harbor perspectives in medicine
  • 2017
  • Corpus ID: 34812753
β-Lactamases, the enzymes that hydrolyze β-lactam antibiotics, remain the greatest threat to the usage of these agents. In this… Expand
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Review
2016
Review
2016
β-Lactams are the most widely used class of antibiotics. Since the discovery of benzylpenicillin in the 1920s, thousands of new… Expand
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