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Penem

National Institutes of Health

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meropenem

Papers overview

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2008
2008
Inhibition of OXA-1 β-Lactamase by Penems
ABSTRACT The partnering of a β-lactam with a β-lactamase inhibitor is a highly effective strategy that can be used to combat… 
1997
1997
SYN-1012: A New β-Lactamase Inhibitor of Penem Skeleton
A new β-lactamase inhibitor, SYN-1012, with a penem skeleton was synthesized and its biological activity compared with clavulanic… 
1994
1994
Kinetic and physical studies of beta-lactamase inhibition by a novel penem, BRL 42715.
The interactions of Staphylococcus aureus, Bacillus cereus I, TEM, Klebsiella pneumoniae K1 and Enterobacter cloacae P99 beta… 
1991
1991
Carbapenem and penem antibiotics. VI. Synthesis and antibacterial activity of 2-heteroaromatic-thiomethyl and 2-carbamoyloxymethyl 1-methylcarbapenems.
The synthesis and antibacterial activity of the 1-methylcarbapenems, 2-heteroaromatic-thiomethyl and 2-carbamoyloxymethyl… 
1987
1987
In vitro activity of CGP 31608, a new penem
The in vitro activity of CGP 31608, a semisynthetic penem derivative, was compared with that of Sch 34343, imipenem, cefoxitin… 
1986
1986
From penicillin to penem and carbapenem. VII. Synthesis and antibacterial activity of penem derivatives.
The azetidinone derivative (6), which has an (R)-hydroxyethyl substituent at the C-3 position, was prepared efficiently from 6… 
1985
1985
The in-vitro activity of a novel penem FCE 22101 compared to other beta-lactam antibiotics.
FCE 22101 is a penem antibiotic which inhibits the majority of Enterobacteriaceae, Haemophilus influenzae, and Neisseria… 
1985
1985
Syntheses and biological activities of new penem derivatives with side chains derived from 4-hydroxyproline.
New penem derivatives with various substituted, enantiomerically pure pyrrolidine-thio side chains at the C-2 position were… 
1985
1985
Carbapenem and penem antibiotics. I. Total synthesis and antibacterial activity of dl-asparenomycins A, B and C and related carbapenem antibiotics.
Racemic carbapenem antibiotics having a 1-(hydroxymethyl) ethylidene side-chain at C-6 [dl-asparenomycins A (54), B (37), C (53… 
1983
1983
Comparison of in vitro activity of FCE 22101, a new penem, with those of other beta-lactam antibiotics
The in vitro activity of FCE 22101, a new semisynthetic penem derivative, was compared with that of ceftriaxone, moxalactam… 
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