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lorcainide

Known as: 4'-chloro-N-(1-isopropyl-4-piperidyl)-2-phenylacetanilide, N-(4-chlorophenyl)-N-(1-(1-methylethyl)- 4-piperidinyl)benzeneacetamide.HCl, lorcainid 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

Anti-Arrhythmia AgentsBenzeneacetamidesPiperidines
lorcainide monohydrochloride

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1988
1988
Effect of SUN 1165, a new potent antiarrhythmic agent, on the kinetics of rate-dependent block of Na channels and ventricular conduction of extrasystoles.
Effects of SUN 1165, disopyramide, lorcainide, and mexiletine were studied either on the kinetics of onset of and recovery from… 
1984
1984
Comparison of lorcainide and quinidine in the treatment of ventricular ectopy.
Lorcainide, a new type I antiarrhythmic agent, was compared to quinidine in respect to antiarrhythmic efficacy and clinical… 
1983
1983
Lorcainide disposition kinetics in arrhythmia patients
Lorcainide disposition kinetics were studied after intravenous and oral administration to patients with ventricular arrhythmias… 
1981
1981
Electrophysiological effects of lorcainide, a new antiarrhythmic drug. Observations in patients with and without pre-excitation.
The electrophysiological effects of the intravenous administration of a new antiarrhythmic drug, lorcainide, were evaluated by… 
Review
1980
Review
1980
Comparative pharmacokinetics of new antiarrhythmic drugs.
Highly Cited
1979
Highly Cited
1979
Lorcainide; II. Plasma concentration‐effect relationship
The effects of lorcainide were studied in 17 patients after single doses (2 mg/kg intravenously; 6 mg/min intravenously over 30… 
Highly Cited
1979
Highly Cited
1979
Lorcainide; I. Saturable presystemic elimination
The disposition of lorcainide after single oral and intravenous doses and during long‐term oral and intravenous dosing was… 
1979
1979
Disposition and antiarrhythmic effect of lorcainide.
The disposition and the antiarrhythmic effect of lorcainide (R 15,889) were investigated in 11 patients with ventricular… 
1979
1979
Electrophysiological Actions of Lorcainide in Patients with Cardiac Disease
Lorcainide is a new antiarrhythmic agent which effectively suppresses ventricular premature contractions. Its… 
1977
1977
Clinical experience with lorcainide (R 15 889), a new anti-arrhythmic drug.
The anti-arrhythmic properties of a new drug, lorcainide, have been evaluated. Lorcainide is highly efficient for the treatment… 
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