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granzyme A

Known as: Cytotoxic T Lymphocyte Proteinase 1, Cytotoxic T-Lymphocyte Proteinase 1, Hanukah Factor 
National Institutes of Health

Related topics

Related topics

3 relations
GZMA gene

Narrower (1)

GZMA protein, human

Broader (1)

Granzymes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
IL‐2‐granzyme A chimeric protein overcomes multidrug resistance (MDR) through a caspase 3‐independent apoptotic pathway
One of the main problems of conventional anticancer therapy is multidrug resistance (MDR), whereby cells acquire resistance to… 
Review
2010
Review
2010
A reactive response to granzyme B
Cytotoxic T lymphocytes (CTLs) fight infection and prevent cancer by killing cells that harbour virus or pose a risk of… 
2009
2009
Response: Granzyme A: cell death–inducing protease, proinflammatory agent, or both?
We recently showed that granzyme A (GzmA) cleaves poly(adenosine 5′-diphosphate-ribose) polymerase-1 (PARP-1) to promote cell… 
2006
2006
Glucocorticoid-induced alternative promoter usage for a novel 5′ variant of granzyme A
AbstractGlucocorticoids exert diverse physiological functions through transcriptional regulation of genes including granzyme A… 
2004
2004
Molecular understanding of oxygen-tension and patient-variability effects on ex vivo expanded T cells.
Immunotherapy with ex vivo cultured T cells depends on a large supply of biologically active cells. Understanding the effects of… 
1993
1993
The human granzyme A (HFSP, CTLA3) gene maps to 5q11-q12 and defines a new locus of the serine protease superfamily.
Human granzyme A (HFSP, Hanukah factor serine protease; CTLA3, cytotoxic T-lymphocyte-associated serine esterase-3), a… 
1992
1992
Transfection of mouse cytotoxic T lymphocyte with an antisense granzyme A vector reduces lytic activity.
Murine CTL have seven serine proteases, known as granzymes, in their lytic granules. Despite considerable effort, convincing… 
1990
1990
Characterization of a novel, human cytotoxic lymphocyte-specific serine protease cDNA clone (CSP-C).
A human cDNA clone encoding a novel serine protease, cytotoxic serine protease-C(CSP-C), has been isolated from a cDNA library… 
1988
1988
Human T cell specific proteinase (HuTSP) is encoded by the T cell and natural killer cell specific human Hanukah factor (HuHF) gene
Highly Cited
1986
Highly Cited
1986
Identification of granzyme A isolated from cytotoxic T‐lymphocyte‐granules as one of the proteases encoded by CTL‐specific genes
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