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GZMA gene

Known as: granzyme 1, GZMA, Cytotoxic T-lymphocyte-associated serine esterase-3 
This gene plays a role in natural killer and T-cell activated cytolysis.
National Institutes of Health

Related topics

Related topics

6 relations
Cell-Mediated CytolysisGZMA protein, humanHydrolysisPositive Regulation of Cytolytic Process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Expression and Function of Granzymes A and B in Escherichia coli Peritonitis and Sepsis
Escherichia (E.) coli is the most common causative pathogen in peritonitis, the second most common cause of sepsis. Granzymes… 
2013
2013
An IP3R3- and NPY-Expressing Microvillous Cell Mediates Tissue Homeostasis and Regeneration in the Mouse Olfactory Epithelium
Calcium-dependent release of neurotrophic factors plays an important role in the maintenance of neurons, yet the release… 
2006
2006
The co‐expression of 2B4 (CD244) and CD160 delineates a subpopulation of human CD8+ T cells with a potent CD160‐mediated cytolytic effector function
Within human CD8+ T lymphocytes, the CD27−CD45RAhigh or CD56+ phenotypes contribute to precisely define the cells with CTL… 
2005
2005
Quiescent and activated mouse granulocytes do not express granzyme A and B or perforin: similarities or differences with human polymorphonuclear leukocytes?
Polymorphonuclear leukocytes have been shown to use a multitude of effector functions to combat pathogens and tumors, including… 
2004
2004
Genetic analysis of H1 linker histone subtypes and their functions in mice.
2004
2004
The genes encoding NK cell granule serine proteases, human tryptase-2 (TRYP2) and human granzyme A (HFSP), both map to chromosome 5q11-q12 and define a new locus for cytotoxic lymphocyte granule…
This submission in the Gene Antigen Register section of Immunogenetics journal describes research in which fluorescence in situ… 
Review
2003
Review
2003
SET-ting the Stage for Life and Death
1999
1999
Commissure formation in the embryonic CNS of Drosophila II . Function of the different midline cells
The majority of neurons in the ventral nerve cord send their axons across the midline to the contralateral side. These neurons… 
1993
1993
The human granzyme A (HFSP, CTLA3) gene maps to 5q11-q12 and defines a new locus of the serine protease superfamily.
Human granzyme A (HFSP, Hanukah factor serine protease; CTLA3, cytotoxic T-lymphocyte-associated serine esterase-3), a… 
Highly Cited
1988
Highly Cited
1988
Characterization of three serine esterases isolated from human IL-2 activated killer cells.
Human peripheral blood mononuclear cells, activated for 14 to 20 days with 1000 U/ml rIL-2, develop strong cytotoxicity for NK… 
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