GZMA gene

Known as: granzyme 1, GZMA, Cytotoxic T-lymphocyte-associated serine esterase-3 
This gene plays a role in natural killer and T-cell activated cytolysis.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1986-2018
05101519862018

Papers overview

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Highly Cited
2007
Highly Cited
2007
Although activated murine NK cells can use the granule exocytosis pathway to kill target cells immediately upon recognition… (More)
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Highly Cited
2005
Highly Cited
2005
Citrobacter rodentium is a bacterial pathogen that causes a murine infectious colitis equivalent to enterohemorrhagic Escherichia… (More)
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Highly Cited
1999
Highly Cited
1999
Analysis of perforin-deficient mice has identified the cytolytic pathway and perforin as the preeminent effector molecule in T… (More)
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Highly Cited
1998
Highly Cited
1998
Activated CTLs and NK cells induce apoptosis via multiple mechanisms, including that termed granule exocytosis. The latter… (More)
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Highly Cited
1998
Highly Cited
1998
Although human immunodeficiency virus (HIV)-infected subjects without acquired immunodeficiency syndrome have a high frequency of… (More)
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Highly Cited
1996
Highly Cited
1996
Cytolytic lymphocytes are of cardinal importance in the recovery from primary viral infections. Both natural killer cells and… (More)
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1996
1996
Granzymes, serine proteases located in the granules of cytotoxic T cel ls and NK cells, are essential for induction of target… (More)
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Highly Cited
1995
Highly Cited
1995
Granzyme A, a granule-associated serine proteinase of activated cytotoxic T cells and natural killer cells, has been reported to… (More)
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Highly Cited
1993
Highly Cited
1993
To investigate the question of whether lytic granules share a common biogenesis with lysosomes, cloned cytolytic T cell lines… (More)
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Highly Cited
1992
Highly Cited
1992
The noncytotoxic rat mast cell tumor line RBL was transfected with genes for the cytotoxic lymphocyte granule proteins cytolysin… (More)
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