fidaxomicin

Known as: Lipiarmicin, Lipiarmycin, Lipiarrmycin 
A narrow-spectrum, 18-membered macrolide antibiotic isolated from the actinomycete Dactylosporangium aurantiacum subsp. hamdenensis with potential… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
BACKGROUND In May 2011, the Food and Drug Administration approved fidaxomicin for the treatment of Clostridium difficile… (More)
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Highly Cited
2012
Highly Cited
2012
BACKGROUND Infection with Clostridium difficile is the primary infective cause of antibiotic-associated diarrhoea. We aimed to… (More)
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Highly Cited
2012
Highly Cited
2012
Recurrence of Clostridium difficile infection (CDI) occurs in approximately 25% of successfully treated patients. Two phase 3… (More)
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Highly Cited
2012
Highly Cited
2012
The microflora-sparing properties of fidaxomicin were examined during the conduct of a randomized clinical trial comparing… (More)
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Highly Cited
2012
Highly Cited
2012
Two recently completed phase 3 trials (003 and 004) showed fidaxomicin to be noninferior to vancomycin for curing Clostridium… (More)
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2012
2012
Fidaxomicin is bactericidal against Clostridium difficile. The combined results of 8 in vitro studies of 1323 C. difficile… (More)
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2012
2012
Fidaxomicin (FDX) is a novel antimicrobial agent with narrow-spectrum and potent bactericidal activity against Clostridium… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Clostridium difficile infection is a serious diarrheal illness associated with substantial morbidity and mortality… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Treatment guidelines recommend stopping all implicated antibiotics at the onset of Clostridium difficile infection… (More)
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Highly Cited
2010
Highly Cited
2010
Clostridium difficile infection (CDI) is the most common identifiable cause of diarrhoea in hospitalized patients. Current… (More)
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