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OPT 80

Known as: OPT-80, OPT80 cpd 
 
National Institutes of Health

Papers overview

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2010
2010
Fidaxomicin (formerly OPT-80) is a narrow-spectrum investigational, nonabsorbed oral agent being developed for the treatment of… Expand
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Highly Cited
2009
Highly Cited
2009
During a 10-day treatment for Clostridium difficile infection, OPT-80 and vancomycin were comparably effective in reducing C… Expand
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Highly Cited
2009
Highly Cited
2009
OPT-80, a novel, minimally absorbed macrocycle, is a candidate treatment option for Clostridium difficile infection (CDI) based… Expand
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2008
2008
Current therapies for Clostridium difficile infection (CDI) are encumbered by treatment failures and recurrences. Due to its high… Expand
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Review
2007
Review
2007
  • Alan Johnson
  • Current opinion in investigational drugs
  • 2007
  • Corpus ID: 42242706
Optimer Pharmaceuticals Inc, in collaboration with Par Pharmaceutical Companies Inc, is developing OPT-80, a narrow-spectrum… Expand
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Highly Cited
2007
Highly Cited
2007
The incidence and severity of Clostridium difficile-associated disease (CDAD) is increasing, and standard treatment is not always… Expand
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Highly Cited
2004
Highly Cited
2004
The activities of OPT-80 against 453 intestinal bacteria were compared with those of seven other drugs. OPT-80 showed good… Expand
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Highly Cited
2004
Highly Cited
2004
Agar dilution MIC was used to compare activities of OPT-80, linezolid, vancomycin, teicoplanin, quinupristin/dalfopristin… Expand
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Highly Cited
2004
Highly Cited
2004
Clostridium difficile remains the major cause of nosocomial diarrhea. Reports on impaired susceptibility of C. difficile to… Expand
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1961
1961
Abb. 5. Schwangerenbetreuung und pei'inatale Si~uglingssterb lichkeit betreut wurden. Wir spraehen yon ,,ausreiehender" bzw… Expand
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