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OPT 80

Known as: OPT-80, OPT80 cpd 
 
National Institutes of Health

Papers overview

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2010
2010
Fidaxomicin (formerly OPT-80) is a narrow-spectrum investigational, nonabsorbed oral agent being developed for the treatment of… Expand
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Highly Cited
2008
Highly Cited
2008
ABSTRACT During a 10-day treatment for Clostridium difficile infection, OPT-80 and vancomycin were comparably effective in… Expand
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Highly Cited
2008
Highly Cited
2008
ABSTRACT OPT-80, a novel, minimally absorbed macrocycle, is a candidate treatment option for Clostridium difficile infection (CDI… Expand
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Highly Cited
2008
Highly Cited
2008
ABSTRACT Current therapies for Clostridium difficile infection (CDI) are encumbered by treatment failures and recurrences. Due to… Expand
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Review
2007
Review
2007
  • A. Johnson
  • Current opinion in investigational drugs
  • 2007
  • Corpus ID: 42242706
Optimer Pharmaceuticals Inc, in collaboration with Par Pharmaceutical Companies Inc, is developing OPT-80, a narrow-spectrum… Expand
Highly Cited
2007
Highly Cited
2007
ABSTRACT The incidence and severity of Clostridium difficile-associated disease (CDAD) is increasing, and standard treatment is… Expand
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Highly Cited
2004
Highly Cited
2004
ABSTRACT The activities of OPT-80 against 453 intestinal bacteria were compared with those of seven other drugs. OPT-80 showed… Expand
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Highly Cited
2004
Highly Cited
2004
ABSTRACT Clostridium difficile remains the major cause of nosocomial diarrhea. Reports on impaired susceptibility of C. difficile… Expand
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Highly Cited
2004
Highly Cited
2004
ABSTRACT Agar dilution MIC was used to compare activities of OPT-80, linezolid, vancomycin, teicoplanin, quinupristin… Expand
1961
1961
  • K. Seidler
  • Archiv für Gynäkologie
  • 1961
  • Corpus ID: 31821399
Abb. 5. Schwangerenbetreuung und pei'inatale Si~uglingssterb lichkeit betreut wurden. Wir spraehen yon ,,ausreiehender" bzw… Expand