• Publications
  • Influence
Clinical Practice Guidelines for Clostridium difficile Infection in Adults: 2010 Update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America
TLDR
This guideline updates recommendations regarding epidemiology, diagnosis, treatment, and infection control and environmental management of Clostridium difficile. Expand
Clostridium difficile infection: new developments in epidemiology and pathogenesis
TLDR
Since 2001, the prevalence and severity of C. difficile infection has increased significantly, which has led to increased research interest and the discovery of new virulence factors, and has expanded and focused the development of new treatment and prevention regimens. Expand
Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of
TLDR
This guideline updates recommendations regarding epidemiology, diagnosis, treatment, infection prevention, and environmental management on Clostridium difficile infection in adults and includes recommendations for children. Expand
The Changing Epidemiology of Clostridium difficile Infections
TLDR
The evidence for the changing epidemiology, clinical virulence and outcome of treatment of CDI is reviewed, and the similarities and differences between data from various countries and continents are reviewed. Expand
Interventions to improve antibiotic prescribing practices for hospital inpatients.
TLDR
The results show that interventions to improve antibiotic prescribing to hospital inpatients are successful, and can reduce antimicrobial resistance or hospital acquired infections. Expand
epic3: National Evidence-Based Guidelines for Preventing Healthcare-Associated Infections in NHS Hospitals in England
TLDR
These guidelines (epic3) provide comprehensive recommendations for preventing HCAI in hospital and other acute care settings based on the best currently available evidence, and the synopses of evidence underpinning the guideline recommendations have been updated. Expand
epic2: National Evidence-Based Guidelines for Preventing Healthcare-Associated Infections in NHS Hospitals in England
TLDR
These updated national guidelines (epic2) provide comprehensive recommendations for preventing HCAI in hospitals and other acute care settings based on the best currently available evidence. Expand
Clostridium difficile infection in Europe: a hospital-based survey
TLDR
The data emphasise the importance of multicountry surveillance to detect and control C difficile infection in Europe and build capacity for diagnosis and surveillance. Expand
Diverse sources of C. difficile infection identified on whole-genome sequencing.
TLDR
Genetically diverse sources, in addition to symptomatic patients, play a major part in C. difficile transmission, which suggests a considerable reservoir of C. Difficile infection identified in health care settings or in the community in Oxfordshire. Expand
Pan-European longitudinal surveillance of antibiotic resistance among prevalent Clostridium difficile ribotypes.
TLDR
There was a significant correlation between lack of ribotype diversity and greater antimicrobial resistance (measured by cumulative resistance score), and well-known epidemic ribotypes 027 and 001/072 were associated with multiple antimacterial resistance, but high levels of resistance were also observed, raising the possibility of antimicrobial exposure as the underlying reason for their appearance. Expand
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