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ertapenem

Known as: (4R,5R,6S)-3-((3S,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-yl)sulfanyl-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, (4R,5S,6S)-3-((3S,5S)-5-((3-Carboxyphenyl)carbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid, (1R,5S,6S,8R,2'S,4's)-2-(2-(3-carboxyphenylcarbamoyl)pyrrolidin-4-ylthio)-6-(1-hydroxyethyl)-1-methylcarbapenem-3-carboxylic acid 
A 1-beta-methyl carbapenem and broad-spectrum beta-lactam antibiotic with bactericidal property. Ertapenem binds to penicillin binding proteins (PBPs… 
National Institutes of Health

Related topics

Related topics

22 relations
Abdominal AbscessBacterial InfectionsBacteroides InfectionsCarbapenems

Broader (2)

Anti-Bacterial Agentsbeta-Lactams

Narrower (2)

Invanzertapenem sodium

Papers overview

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2016
2016
In silico analysis of hotspot mutations in the bacterial NDM-1 and KPC-1 carbapenemases that cause severe MDR phenotypes
Multi-drug resistant bacterial β-lactamases evolve rapidly with hundreds of mutations as in TEM and OXA variants. More than… 
2016
2016
Resultados de la vigilancia nacional de resistencia antimicrobiana en infecciones asociadas a la atención en salud en enterobacterias y Gram negativos no fermentadores, Colombia 2012-2014
Introduction. From the third quarter of 2012 the National System monitoring antimicrobial resistance in Associated Infection… 
2015
2015
Study of variables involved in hospital-acquired urinary tract infections at a university hospital
OBJECTIVE: Analyze bacteria involved in urinary tract nosocomial infections (UTIs), their sensitivity profile, and other… 
2015
2015
Comparison of four phenotypic tests, three biochemical tests and Cepheid Xpert Carba-R for detection of carbapenemase enzymes in Gram-negative bacteria
Background and aims: The increased consumption of carbapenems has resulted in the consequent increase in the level of carbapenem… 
2015
2015
VIM-2 carbapenemase-producing Pseudomonas aeruginosa in a patient from Port Elizabeth, South Africa.
We report on the emergence of a multidrug-resistant Pseudomonas aeruginosa isolate in a public hospital in Port Elizabeth… 
2012
2012
Antibiotic Sensitivity and Phenotypic Detection Of ESBL producing E.Coli Strains Causing Urinary Tract Infection In a Community Hospital, Chennai,
Urinary Tract Infection (UTI) forms the largest single group of hospital acquired infections and account for about 40-50% of the… 
2011
2011
Pharmacokinetics of free ertapenem in critically ill septic patients: intermittent versus continuous infusion.
BACKGROUND The aim of this paper was to compare the pharmacokinetic and pharmacodynamic (PK/PD) parameters of continuous (CI) and… 
2009
2009
Contribution of OmpK 36 to carbapenem susceptibility in KPC-producing Klebsiella pneumoniae
Received 2 May 2009 Accepted 23 June 2009 Isolates of Klebsiella pneumoniae harbouring the carbapenemase KPC may have carbapenem… 
2005
2005
In vitro activity of ertapenem against bacteraemic pneumococci: report of a French multicentre study including 339 strains.
has been also observed in the USA, where Wang et al. 8 demonstrated that 27% of pig strains were resistant and Taylor & Courvalin… 
2004
2004
Management of Complicated Appendicitis and Comparison of Outcome with Other Primary Sites of Intra-abdominal Infection: Results of a Trial Comparing Ertapenem and Piperacillin-Tazobactam
Abstract A post-hoc analysis of data from a trial of complicated intra-abdominal infection was performed to compare the…