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beta-Lactams

Known as: beta-Lactams [Chemical/Ingredient], beta Lactams, Beta-lactam 
Four-membered cyclic AMIDES, best known for the PENICILLINS based on a bicyclo-thiazolidine, as well as the CEPHALOSPORINS based on a bicyclo… 
National Institutes of Health

Related topics

Related topics

18 relations

Broader (2)

Anti-Bacterial AgentsLactams

Narrower (9)

CA-104Disodium LatamoxefRX-10100T 5575
In BloodPoisoning by cefalosporins and other beta-lactam antibioticsagonistsantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Characterization of a New Metallo-β-Lactamase Gene, blaNDM-1, and a Novel Erythromycin Esterase Gene Carried on a Unique Genetic Structure in Klebsiella pneumoniae Sequence Type 14 from India
ABSTRACT A Swedish patient of Indian origin traveled to New Delhi, India, and acquired a urinary tract infection caused by a… 
Review
2007
Review
2007
Carbapenemases: the Versatile β-Lactamases
SUMMARY Carbapenemases are β-lactamases with versatile hydrolytic capacities. They have the ability to hydrolyze penicillins… 
Review
2003
Review
2003
Leptospirosis: a zoonotic disease of global importance.
Review
2003
Review
2003
Diagnosis of immediate allergic reactions to beta‐lactam antibiotics
Allergic reactions to betalactams are the most common cause of adverse drug reactions mediated by specific immunological… 
Review
1995
Review
1995
beta-Lactamases in laboratory and clinical resistance
  • D. Livermore
  • Clinical microbiology reviews
  • 1995
  • Corpus ID: 5002087
beta-Lactamases are the commonest single cause of bacterial resistance to beta-lactam antibiotics. Numerous chromosomal and… 
Highly Cited
1988
Highly Cited
1988
Extended broad-spectrum beta-lactamases conferring transferable resistance to newer beta-lactam agents in Enterobacteriaceae: hospital prevalence and susceptibility patterns.
Before 1985 at the Pitié-Salpêtrière Hospital in Paris (2,400 beds), resistance to cefotaxime in clinical isolates of… 
Highly Cited
1984
Highly Cited
1984
Low-affinity penicillin-binding protein associated with beta-lactam resistance in Staphylococcus aureus
Methicillin resistance in Staphylococcus aureus has been associated with alterations in the penicillin-binding proteins (PBPs… 
Highly Cited
1980
Highly Cited
1980
The structure of beta-lactamases.
  • R. Ambler
  • Philosophical transactions of the Royal Society…
  • 1980
  • Corpus ID: 32518904
The beta-lactamases are widely distributed in both Gram-positive and Gram-negative bacteria. They all inactivate penicillins and… 
Highly Cited
1977
Highly Cited
1977
Clavulanic Acid: a Beta-Lactamase-Inhibiting Beta-Lactam from Streptomyces clavuligerus
A novel β-lactamase inhibitor has been isolated from Streptomyces clavuligerus ATCC 27064 and given the name clavulanic acid… 
Highly Cited
1972
Highly Cited
1972
Novel Method for Detection of β-Lactamases by Using a Chromogenic Cephalosporin Substrate
A new cephalosporin with a highly reactive β-lactam ring was found to give an immediate color change in the presence of… 
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