Antimicrobial susceptibility of Enterobacteriaceae, including molecular characterization of extended-spectrum beta-lactamase-producing species, in urinary tract isolates from hospitalized patients in North America and Europe: results from the SMART study 2009-2010.

@article{Hoban2012AntimicrobialSO,
  title={Antimicrobial susceptibility of Enterobacteriaceae, including molecular characterization of extended-spectrum beta-lactamase-producing species, in urinary tract isolates from hospitalized patients in North America and Europe: results from the SMART study 2009-2010.},
  author={Daryl J. Hoban and Christine Lascols and Lindsay E. Nicolle and Robert E. Badal and Samuel K Bouchillon and Meredith A M Hackel and Stephen P Hawser},
  journal={Diagnostic microbiology and infectious disease},
  year={2012},
  volume={74 1},
  pages={62-7}
}
In 2009-2010, 3646 urinary tract isolates of Enterobacteriaceae spp. were isolated from hospitalized patients in North America and Europe. Extended-spectrum beta-lactamase (ESBL) production was detected in 8.5% and 8.8% of Escherichia coli and Klebsiella pneumoniae, respectively, in North America and in 17.6% and 38.9% for Europe, respectively. The carbapenems (ertapenem and imipenem) were the most active agents in vitro, with ampicillin-sulbactam the least active. Molecular characterization of… CONTINUE READING