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epigallocatechin gallate

Known as: Epigallocatechin-3-Gallate, epigallocatechin-3-O-gallate, EGCG 
A phenolic antioxidant found in a number of plants such as green and black tea. It inhibits cellular oxidation and prevents free radical damage to… 
National Institutes of Health

Related topics

Related topics

15 relations

Broader (7)

Anticarcinogenic AgentsAntimutagenic AgentsAntioxidantsCatechin
Ethanol 0.7 ML/ML Topical GelZinc Oxide 120 MG/ML Topical CreamZinc Oxide 130 MG/ML Topical Creamanalogs & derivatives

Narrower (4)

Kunecatechins Ointmentepigallocatechin gallate palmitatesepigallocatechin gallate stearatespolyphenon E

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Epigallocatechin-3-gallate, a histone acetyltransferase inhibitor, inhibits EBV-induced B lymphocyte transformation via suppression of RelA acetylation.
Because the p300/CBP-mediated hyperacetylation of RelA (p65) is critical for nuclear factor-kappaB (NF-kappaB) activation, the… 
Highly Cited
2007
Highly Cited
2007
Epigallocatechin-3-gallate (EGCG), A Green Tea Polyphenol, Suppresses Hepatic Gluconeogenesis through 5′-AMP-activated Protein Kinase*
Epigallocatechin-3-gallate (EGCG), a main catechin of green tea, has been suggested to inhibit hepatic gluconeogenesis. However… 
Highly Cited
2006
Highly Cited
2006
Epigallocatechin gallate supplementation alleviates diabetes in rodents.
As the prevalence of type 2 diabetes mellitus is increasing at an alarming rate, effective nutritional and exercise strategies… 
Highly Cited
2004
Highly Cited
2004
Green Tea Epigallocatechin-3-Gallate Mediates T Cellular NF-κB Inhibition and Exerts Neuroprotection in Autoimmune Encephalomyelitis1
Recent studies in multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis (EAE), point to the fact… 
Highly Cited
2003
Highly Cited
2003
Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon E in healthy individuals.
PURPOSE Green tea and green tea polyphenols have been shown to possess cancer preventive activities in preclinical model systems… 
Highly Cited
2003
Highly Cited
2003
Enzymology of methylation of tea catechins and inhibition of catechol-O-methyltransferase by (-)-epigallocatechin gallate.
(-)-Epigallocatechin gallate (EGCG) and (-)-epigallocatechin (EGC) are the major polyphenolic constituents in green tea. In this… 
Highly Cited
2002
Highly Cited
2002
Epigallocatechin Gallate, a Constituent of Green Tea, Represses Hepatic Glucose Production*
Herbs have been used for medicinal purposes, including the treatment of diabetes, for centuries. Plants containing flavonoids are… 
Highly Cited
2002
Highly Cited
2002
Stability, cellular uptake, biotransformation, and efflux of tea polyphenol (-)-epigallocatechin-3-gallate in HT-29 human colon adenocarcinoma cells.
The biological effects of (-)-epigallocatechin-3-gallate (EGCG) have been extensively investigated in cell lines, but its… 
Highly Cited
2002
Highly Cited
2002
Involvement of Protein Kinase C Activation and Cell Survival/ Cell Cycle Genes in Green Tea Polyphenol (−)-Epigallocatechin 3-Gallate Neuroprotective Action*
Studies from our laboratory have demonstrated that the major green tea polyphenol, (−)-epigallocatechin 3-gallate (EGCG), exerts… 
Highly Cited
2001
Highly Cited
2001
Green tea polyphenol (-)-epigallocatechin-3-gallate treatment of human skin inhibits ultraviolet radiation-induced oxidative stress.
The use of naturally occurring botanicals with substantial antioxidant activity to afford protection to human skin against UV… 
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