epigallocatechin gallate

Known as: Epigallocatechin-3-Gallate, epigallocatechin-3-O-gallate, EGCG 
A phenolic antioxidant found in a number of plants such as green and black tea. It inhibits cellular oxidation and prevents free radical damage to… (More)
National Institutes of Health

Related topics

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14 relations

Broader (7)

Anticarcinogenic AgentsAntimutagenic AgentsAntioxidantsCatechin
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Ethanol 0.7 ML/ML Topical GelZinc Oxide 130 MG/ML Topical Creamanalogs & derivatives

Narrower (4)

Kunecatechins Ointmentepigallocatechin gallate palmitatesepigallocatechin gallate stearatespolyphenon E

Papers overview

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Review
2017
Review
2017
Targeting the TLR4 signaling pathway by polyphenols: A novel therapeutic strategy for neuroinflammation
A wide array of cell signaling mediators and their interactions play vital roles in neuroinflammation associated with ischemia… (More)
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Highly Cited
2006
Highly Cited
2006
Epigallocatechin gallate supplementation alleviates diabetes in rodents.
As the prevalence of type 2 diabetes mellitus is increasing at an alarming rate, effective nutritional and exercise strategies… (More)
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Highly Cited
2005
Highly Cited
2005
Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice.
Alzheimer's disease (AD) is a progressive neurodegenerative disorder pathologically characterized by deposition of beta-amyloid… (More)
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Highly Cited
2003
Highly Cited
2003
Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines.
Hypermethylation of CpG islands in the promoter regions is an important mechanism to silence the expression of many important… (More)
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Highly Cited
2003
Highly Cited
2003
Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon E in healthy individuals.
PURPOSE Green tea and green tea polyphenols have been shown to possess cancer preventive activities in preclinical model systems… (More)
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Highly Cited
2002
Highly Cited
2002
Epigallocatechin gallate, a constituent of green tea, represses hepatic glucose production.
Herbs have been used for medicinal purposes, including the treatment of diabetes, for centuries. Plants containing flavonoids are… (More)
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Highly Cited
2001
Highly Cited
2001
Phase I pharmacokinetic study of tea polyphenols following single-dose administration of epigallocatechin gallate and polyphenon E.
Green tea has been shown to exhibit cancer-preventive activities in preclinical studies. Its principal active components include… (More)
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Highly Cited
2000
Highly Cited
2000
Modulation of endocrine systems and food intake by green tea epigallocatechin gallate.
Green tea polyphenols, especially the catechin, (-)-epigallocatechin gallate (EGCG), have been proposed as a cancer… (More)
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Highly Cited
1998
Highly Cited
1998
Wide distribution of [3H](-)-epigallocatechin gallate, a cancer preventive tea polyphenol, in mouse tissue.
The increasing recognition of green tea and tea polyphenols as cancer preventives has created a need for a study of their… (More)
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Highly Cited
1997
Highly Cited
1997
Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells.
BACKGROUND AND PURPOSE The polyphenolic compounds present in green tea show cancer chemopreventive effects in many animal tumor… (More)
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