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epigallocatechin gallate

Known as: Epigallocatechin-3-Gallate, epigallocatechin-3-O-gallate, EGCG 
A phenolic antioxidant found in a number of plants such as green and black tea. It inhibits cellular oxidation and prevents free radical damage to… 
National Institutes of Health

Related topics

Related topics

15 relations

Broader (7)

Anticarcinogenic AgentsAntimutagenic AgentsAntioxidantsCatechin
Ethanol 0.7 ML/ML Topical GelZinc Oxide 120 MG/ML Topical CreamZinc Oxide 130 MG/ML Topical Creamanalogs & derivatives

Narrower (4)

Kunecatechins Ointmentepigallocatechin gallate palmitatesepigallocatechin gallate stearatespolyphenon E

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Green tea catechin, epigallocatechin-3-gallate (EGCG): mechanisms, perspectives and clinical applications.
Review
2006
Review
2006
Targeting multiple signaling pathways by green tea polyphenol (-)-epigallocatechin-3-gallate.
Cell signaling pathways, responsible for maintaining a balance between cell proliferation and death, have emerged as rational… 
Review
2005
Review
2005
Antimicrobial activity of flavonoids
Highly Cited
2005
Highly Cited
2005
Green Tea Epigallocatechin-3-Gallate (EGCG) Modulates Amyloid Precursor Protein Cleavage and Reduces Cerebral Amyloidosis in Alzheimer Transgenic Mice
Alzheimer's disease (AD) is a progressive neurodegenerative disorder pathologically characterized by deposition of β-amyloid (A… 
Highly Cited
2003
Highly Cited
2003
Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines.
Hypermethylation of CpG islands in the promoter regions is an important mechanism to silence the expression of many important… 
Highly Cited
2003
Highly Cited
2003
Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon E in healthy individuals.
PURPOSE Green tea and green tea polyphenols have been shown to possess cancer preventive activities in preclinical model systems… 
Highly Cited
2002
Highly Cited
2002
Pharmacokinetics of tea catechins after ingestion of green tea and (-)-epigallocatechin-3-gallate by humans: formation of different metabolites and individual variability.
Green tea and tea polyphenols have been studied extensively as cancer chemopreventive agents in recent years. The bioavailability… 
Highly Cited
2000
Highly Cited
2000
Modulation of endocrine systems and food intake by green tea epigallocatechin gallate.
Green tea polyphenols, especially the catechin, (-)-epigallocatechin gallate (EGCG), have been proposed as a cancer… 
Highly Cited
1998
Highly Cited
1998
Wide distribution of [3H](-)-epigallocatechin gallate, a cancer preventive tea polyphenol, in mouse tissue.
The increasing recognition of green tea and tea polyphenols as cancer preventives has created a need for a study of their… 
Highly Cited
1997
Highly Cited
1997
Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells.
BACKGROUND AND PURPOSE The polyphenolic compounds present in green tea show cancer chemopreventive effects in many animal tumor… 
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