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epigallocatechin gallate
Known as:
Epigallocatechin-3-Gallate
, epigallocatechin-3-O-gallate
, EGCG
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A phenolic antioxidant found in a number of plants such as green and black tea. It inhibits cellular oxidation and prevents free radical damage to…
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National Institutes of Health
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Related topics
Related topics
15 relations
Broader (7)
Anticarcinogenic Agents
Antimutagenic Agents
Antioxidants
Catechin
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Ethanol 0.7 ML/ML Topical Gel
Zinc Oxide 120 MG/ML Topical Cream
Zinc Oxide 130 MG/ML Topical Cream
analogs & derivatives
Narrower (4)
Kunecatechins Ointment
epigallocatechin gallate palmitates
epigallocatechin gallate stearates
polyphenon E
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Green tea catechin, epigallocatechin-3-gallate (EGCG): mechanisms, perspectives and clinical applications.
Brahma N. Singh
,
S. Shankar
,
R. K Srivastava
Biochemical Pharmacology
2011
Corpus ID: 27948539
Review
2006
Review
2006
Targeting multiple signaling pathways by green tea polyphenol (-)-epigallocatechin-3-gallate.
N. Khan
,
F. Afaq
,
M. Saleem
,
N. Ahmad
,
H. Mukhtar
Cancer Research
2006
Corpus ID: 5337105
Cell signaling pathways, responsible for maintaining a balance between cell proliferation and death, have emerged as rational…
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Review
2005
Review
2005
Antimicrobial activity of flavonoids
Tim Cushnie
,
A. J. Lamb
International Journal of Antimicrobial Agents
2005
Corpus ID: 4584376
Highly Cited
2005
Highly Cited
2005
Green Tea Epigallocatechin-3-Gallate (EGCG) Modulates Amyloid Precursor Protein Cleavage and Reduces Cerebral Amyloidosis in Alzheimer Transgenic Mice
K. Rezai-zadeh
,
D. Shytle
,
+10 authors
Jun Tan
Journal of Neuroscience
2005
Corpus ID: 18167913
Alzheimer's disease (AD) is a progressive neurodegenerative disorder pathologically characterized by deposition of β-amyloid (A…
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Highly Cited
2003
Highly Cited
2003
Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines.
M. Fang
,
Yimin Wang
,
+5 authors
Chung S. Yang
Cancer Research
2003
Corpus ID: 45637852
Hypermethylation of CpG islands in the promoter regions is an important mechanism to silence the expression of many important…
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Highly Cited
2003
Highly Cited
2003
Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon E in healthy individuals.
H. Chow
,
Yan Cai
,
+6 authors
D. Alberts
Clinical Cancer Research
2003
Corpus ID: 25642078
PURPOSE Green tea and green tea polyphenols have been shown to possess cancer preventive activities in preclinical model systems…
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Highly Cited
2002
Highly Cited
2002
Pharmacokinetics of tea catechins after ingestion of green tea and (-)-epigallocatechin-3-gallate by humans: formation of different metabolites and individual variability.
Mao‐Jung Lee
,
P. Maliakal
,
+6 authors
Chung S. Yang
Cancer Epidemiology, Biomarkers and Prevention
2002
Corpus ID: 22530475
Green tea and tea polyphenols have been studied extensively as cancer chemopreventive agents in recent years. The bioavailability…
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Highly Cited
2000
Highly Cited
2000
Modulation of endocrine systems and food intake by green tea epigallocatechin gallate.
Y. Kao
,
R. Hiipakka
,
S. Liao
Endocrinology
2000
Corpus ID: 17845682
Green tea polyphenols, especially the catechin, (-)-epigallocatechin gallate (EGCG), have been proposed as a cancer…
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Highly Cited
1998
Highly Cited
1998
Wide distribution of [3H](-)-epigallocatechin gallate, a cancer preventive tea polyphenol, in mouse tissue.
M. Suganuma
,
S. Okabe
,
M. Oniyama
,
Y. Tada
,
H. Ito
,
H. Fujiki
Carcinogenesis
1998
Corpus ID: 1890768
The increasing recognition of green tea and tea polyphenols as cancer preventives has created a need for a study of their…
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Highly Cited
1997
Highly Cited
1997
Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells.
N. Ahmad
,
D. Feyes
,
A. Nieminen
,
R. Agarwal
,
H. Mukhtar
Journal of the National Cancer Institute
1997
Corpus ID: 15535308
BACKGROUND AND PURPOSE The polyphenolic compounds present in green tea show cancer chemopreventive effects in many animal tumor…
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