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epigallocatechin gallate

Known as: Epigallocatechin-3-Gallate, epigallocatechin-3-O-gallate, EGCG 
A phenolic antioxidant found in a number of plants such as green and black tea. It inhibits cellular oxidation and prevents free radical damage to… Expand
National Institutes of Health

Related topics

Related topics

15 relations

Broader (7)

Anticarcinogenic AgentsAntimutagenic AgentsAntioxidantsCatechin
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Ethanol 0.7 ML/ML Topical GelZinc Oxide 120 MG/ML Topical CreamZinc Oxide 130 MG/ML Topical Creamanalogs & derivatives

Narrower (4)

Kunecatechins Ointmentepigallocatechin gallate palmitatesepigallocatechin gallate stearatespolyphenon E

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Long non-coding RNAs are emerging targets of phytochemicals for cancer and other chronic diseases
The long non-coding RNAs (lncRNAs) are the crucial regulators of human chronic diseases. Therefore, approaches such as antisense… Expand
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Review
2019
Review
2019
Recent Advances in the Understanding of the Health Benefits and Molecular Mechanisms Associated with Green Tea Polyphenols.
Tea, leaf, or bud from the plant Camellia sinensis, make up some of the beverages popularly consumed in different parts of the… Expand
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Review
2018
Review
2018
Tea Polyphenols in Promotion of Human Health
Tea is the most widely used beverage worldwide. Japanese and Chinese people have been drinking tea for centuries and in Asia, it… Expand
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Review
2018
Review
2018
Nrf2 at the heart of oxidative stress and cardiac protection.
The NFE2L2 gene encodes the transcription factor Nrf2 best known for regulating the expression of antioxidant and detoxification… Expand
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Review
2018
Review
2018
Cancer Prevention with Green Tea and Its Principal Constituent, EGCG: from Early Investigations to Current Focus on Human Cancer Stem Cells
Cancer preventive activities of green tea and its main constituent, (−)-epigallocatechin gallate (EGCG) have been extensively… Expand
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Highly Cited
2005
Highly Cited
2005
Green Tea Epigallocatechin-3-Gallate (EGCG) Modulates Amyloid Precursor Protein Cleavage and Reduces Cerebral Amyloidosis in Alzheimer Transgenic Mice
Alzheimer's disease (AD) is a progressive neurodegenerative disorder pathologically characterized by deposition of β-amyloid (A… Expand
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Highly Cited
2003
Highly Cited
2003
Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines.
Hypermethylation of CpG islands in the promoter regions is an important mechanism to silence the expression of many important… Expand
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Highly Cited
2003
Highly Cited
2003
Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon E in healthy individuals.
PURPOSE Green tea and green tea polyphenols have been shown to possess cancer preventive activities in preclinical model systems… Expand
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Highly Cited
2002
Highly Cited
2002
Pharmacokinetics of tea catechins after ingestion of green tea and (-)-epigallocatechin-3-gallate by humans: formation of different metabolites and individual variability.
Green tea and tea polyphenols have been studied extensively as cancer chemopreventive agents in recent years. The bioavailability… Expand
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Highly Cited
1997
Highly Cited
1997
Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells.
BACKGROUND AND PURPOSE The polyphenolic compounds present in green tea show cancer chemopreventive effects in many animal tumor… Expand
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