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edelfosine
Known as:
Edelfosinum
, ET-18-O-methyl
, 1-octadecyl-2-methylglycero-3-phosphocholine
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A synthetic analog of lysophosphatidylcholine, an ether lipid, possessing anti-leishmanial and antineoplastic activity. The mechanism of action for…
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National Institutes of Health
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Related topics
Related topics
6 relations
3-octadecyl-2-methylglycero-1-phosphocholine
NCIt Antineoplastic Agent Terminology
Broader (3)
Antineoplastic Agents
Phosphodiesterase Inhibitors
Phospholipid Ethers
Narrower (1)
TLC ELL-12
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Liquid Crystal Based Optical Sensor for Imaging Trypsin Activity at Interfaces Between Aqueous Phases and Thermotropic Liquid Crystals
Minmin Zhang
,
Chang-Hyun Jang
2013
Corpus ID: 54205991
In this study, we developed a liquid crystal (LC)-based optical sensor for monitoring enzymatic activity through orientational…
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2002
2002
A Study of Binary Phospholipid Mixtures at the Air−Water Interface Using Infrared Reflection−Absorption Spectroscopy and 2D IR βν Correlation Analysis†
D. Elmore
,
and Saratchandra Shanmukh
,
R. Dluhy
2002
Corpus ID: 23019586
Infrared reflection−absorption spectroscopy (IRRAS) in combination with isotopic substitution and a modified 2D IR correlation…
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1997
1997
Growth inhibitory effects of liposome-associated 1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine
A. Peters
,
I. Ahmad
,
A. Janoff
,
M. Pushkareva
,
E. Mayhew
Lipids
1997
Corpus ID: 4044189
The growth inhibitory effects of 1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine (ET-18-OCH3) and various liposome…
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1992
1992
Preclinical activity of ilmofosine against human tumor colony forming units in vitro
A. Hanauske
,
D. Degen
,
M. Marshall
,
S. Hilsenbeck
,
J. Mcphillips
,
Daniel D Von Holf
Anti-Cancer Drugs
1992
Corpus ID: 25712462
Ilmofosine (BM 41.440, 1-hexadecylthio-2-methoxymethyl-rac-glycero-3-phosphocholine) is a synthetic alkyl lysophospholipid analog…
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1989
1989
Synthesis and antitumor activity of new amphiphilic alkylglycerolipids substituted with a polar head group, 2-(2-trimethylammonioethoxy)ethyl or a congeneric oligo(ethyleneoxy)ethyl group.
K. Ukawa
,
E. Imamiya
,
+7 authors
I. Kudo
Chemical and pharmaceutical bulletin
1989
Corpus ID: 22824440
A new series of amphiphilic 1-octadecyl glycerolipids (eleven compounds, 1a-k) were designed and synthesized, in which the 3…
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1987
1987
Pharmacokinetics of the thioether phospholipid analogue BM 41.440 in rats
D. Herrmann
,
E. Besenfelder
,
U. Bicker
,
W. Pahlke
,
E. Böhm
Lipids
1987
Corpus ID: 4050359
BM 41.440 (1-hexadecylmercapto-2-methoxymethyl-rac-glycero-3-phosphocholine) is a cytotoxic thioether phospholipid analogue that…
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1987
1987
Inhibition of human tumor colony formation by the new alkyl lysophospholipid ilmofosine.
H. Neumann
,
D. Herrmann
,
D. Boerner
Journal of the National Cancer Institute
1987
Corpus ID: 22316927
The cytostatic-cytotoxic effect of the new thioether alkyl lysophospholipid analogue Ilmofosine (1-hexadecylthio-2-methoxymethyl…
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1987
1987
Modulation of chemical carcinogenesis in rats by alkyl lysophospholipids
M. Berger
,
D. Schmähl
Lipids
1987
Corpus ID: 37778853
The influence of 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine (ET-18-OCH3) and 1-hexadecylmercapto-2-methoxymethyl-rac…
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1986
1986
Interaction of lipoprotein lipase with phospholipid vesicles: effect on protein and lipid structure.
L. McLean
,
W. J. Larsen
,
R. Jackson
Biochemistry
1986
Corpus ID: 19377907
The interaction of lipoprotein lipase (LpL) and a nonhydrolyzable phosphatidylcholine, 1,2-ditetradecyl-rac-glycero-3…
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1984
1984
Effect of lysolecithin analogues on plant viruses.
S. Kluge
,
P. Nuhn
,
N. P. Kertscher
,
B. Dobner
Acta virologica
1984
Corpus ID: 41628509
Newly synthesized lysolecithin analogues 2-0-hexadecyl-glycero-3-phosphocholine (1) and its methyl (2), ethyl (3) and benzyl (4…
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