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edelfosine

Known as: Edelfosinum, ET-18-O-methyl, 1-octadecyl-2-methylglycero-3-phosphocholine 
A synthetic analog of lysophosphatidylcholine, an ether lipid, possessing anti-leishmanial and antineoplastic activity. The mechanism of action for… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Leptin can exert its potent appetite-suppressing effects via activation of hypothalamic proopiomelanocortin (POMC) neurons. It… Expand
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Highly Cited
2007
Highly Cited
2007
Multiple myeloma (MM) is an incurable B-cell malignancy, requiring new therapeutic strategies. We have found that synthetic alkyl… Expand
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Highly Cited
2006
Highly Cited
2006
The properties of two oxidatively modified phospholipids viz. 1-palmitoyl-2-(9'-oxo-nonanoyl)-sn-glycero-3-phosphocholine… Expand
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Highly Cited
2005
Highly Cited
2005
Central nervous system responses to cannabis are primarily mediated by CB(1) receptors, which couple preferentially to G(i/o) G… Expand
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Highly Cited
2002
Highly Cited
2002
The sensitivities of both promastigote and amastigote stages of six species of Leishmania, L. donovani, L. major, L. tropica, L… Expand
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Highly Cited
2001
Highly Cited
2001
The antitumor ether lipid ET-18-OCH(3) promotes apoptosis in tumor cells through intracellular activation of Fas/CD95. Results of… Expand
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Highly Cited
1995
Highly Cited
1995
Vesicular stomatitis and rabies viruses enter cells through receptor-mediated endocytosis, followed by fusion of the viral with… Expand
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Highly Cited
1994
Highly Cited
1994
Oxidizability of lipids in homogeneous solution varies linearly with the extent of their unsaturation. In vitro cellular, as well… Expand
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Highly Cited
1990
Highly Cited
1990
The influence of cholesterol on the phase behavior of glycerophospholipids and sphingomyelins was investigated by spin-label… Expand
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Highly Cited
1989
Highly Cited
1989
The influence of electric surface charges on the polar headgroups and the hydrocarbon region of phospholipid membranes was… Expand
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