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edelfosine
Known as:
Edelfosinum
, ET-18-O-methyl
, 1-octadecyl-2-methylglycero-3-phosphocholine
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A synthetic analog of lysophosphatidylcholine, an ether lipid, possessing anti-leishmanial and antineoplastic activity. The mechanism of action for…
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National Institutes of Health
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Related topics
Related topics
6 relations
3-octadecyl-2-methylglycero-1-phosphocholine
NCIt Antineoplastic Agent Terminology
Broader (3)
Antineoplastic Agents
Phosphodiesterase Inhibitors
Phospholipid Ethers
Narrower (1)
TLC ELL-12
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2000
2000
p 38 MAP Kinase Is Required for Vasopressin-Stimulated HSP 27 Induction in Aortic Smooth Muscle Cells
Takeshi Ito
,
O. Kozawa
,
+6 authors
T. Uematsu
2000
Corpus ID: 7344836
We previously showed that arginine vasopressin (AVP) stimulates heat shock protein 27 (HSP27) induction through protein kinase C…
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1992
1992
Preclinical activity of ilmofosine against human tumor colony forming units in vitro
A. Hanauske
,
D. Degen
,
M. Marshall
,
S. Hilsenbeck
,
J. Mcphillips
,
Daniel D Von Holf
Anti-Cancer Drugs
1992
Corpus ID: 25712462
Ilmofosine (BM 41.440, 1-hexadecylthio-2-methoxymethyl-rac-glycero-3-phosphocholine) is a synthetic alkyl lysophospholipid analog…
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1989
1989
Synthesis and antitumor activity of new amphiphilic alkylglycerolipids substituted with a polar head group, 2-(2-trimethylammonioethoxy)ethyl or a congeneric oligo(ethyleneoxy)ethyl group.
K. Ukawa
,
E. Imamiya
,
+7 authors
I. Kudo
Chemical and pharmaceutical bulletin
1989
Corpus ID: 22824440
A new series of amphiphilic 1-octadecyl glycerolipids (eleven compounds, 1a-k) were designed and synthesized, in which the 3…
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1987
1987
Pharmacokinetics of the thioether phospholipid analogue BM 41.440 in rats
D. Herrmann
,
E. Besenfelder
,
U. Bicker
,
W. Pahlke
,
E. Böhm
Lipids
1987
Corpus ID: 4050359
BM 41.440 (1-hexadecylmercapto-2-methoxymethyl-rac-glycero-3-phosphocholine) is a cytotoxic thioether phospholipid analogue that…
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1987
1987
Modulation of chemical carcinogenesis in rats by alkyl lysophospholipids
M. Berger
,
D. Schmähl
Lipids
1987
Corpus ID: 37778853
The influence of 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine (ET-18-OCH3) and 1-hexadecylmercapto-2-methoxymethyl-rac…
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1987
1987
Loss of infectivity of red clover mottle virus by lysolecithin.
S. Kluge
,
K. Gawrisch
,
P. Nuhn
Acta virologica
1987
Corpus ID: 34846353
2-0-hexadecyl-glycero-3-phosphocholine (GPC) 1 mmol/l solution reduced the infectivity of red clover mottle virus (RCMV) by over…
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1987
1987
Immunomodulatory and therapeutic properties of alkyl lysophospholipids in mice
J. Talmadge
,
M. Schneider
,
B. Lenz
,
H. Phillips
,
C. Long
Lipids
1987
Corpus ID: 4002401
This paper describes the immunomodulatory and therapeutic properties of the alkyl lysophospholipids [ALP; 1-O-octadecyl-2-O-rac…
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1986
1986
Interaction of lipoprotein lipase with phospholipid vesicles: effect on protein and lipid structure.
L. McLean
,
W. J. Larsen
,
R. Jackson
Biochemistry
1986
Corpus ID: 19377907
The interaction of lipoprotein lipase (LpL) and a nonhydrolyzable phosphatidylcholine, 1,2-ditetradecyl-rac-glycero-3…
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1985
1985
Synthesis of phosphatidylcholine analogs with an alkyl group at C1 or C3 of the glycerol moiety.
N. Witzke
,
R. Bittman
Journal of Lipid Research
1985
Corpus ID: 11256330
The syntheses of 1,2-di-(O-hexadecyl)-rac-glycero-3-phosphocholines containing a methyl group at either C1 or C3 of the glycerol…
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1984
1984
Effect of lysolecithin analogues on plant viruses.
S. Kluge
,
P. Nuhn
,
N. P. Kertscher
,
B. Dobner
Acta virologica
1984
Corpus ID: 41628509
Newly synthesized lysolecithin analogues 2-0-hexadecyl-glycero-3-phosphocholine (1) and its methyl (2), ethyl (3) and benzyl (4…
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