• Publications
  • Influence
Postjunctional supersensitivity and subsensitivity of excitable tissues to drugs.
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The effects of subacute administration of anticholinesterase insecticides on hepatic microsomal metabolism
Abstract Subacute administration of parathion, paraoxon, disulfoton and carbaryl produces a decrease in hexobarbital sleeping time and an increase in the rate of metabolism of hexobarbital andExpand
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Preclinical activity of ilmofosine against human tumor colony forming units in vitro
Ilmofosine (BM 41.440, 1-hexadecylthio-2-methoxymethyl-rac-glycero-3-phosphocholine) is a synthetic alkyl lysophospholipid analog with activity against a variety of tumor models in vitro and in vivo.Expand
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Effects of Carvedilol on Blood Pressure in Patients with Mild to Moderate Hypertension
SummaryCarvedilol 12.5, 25 and 50mg was administered once daily for 4 weeks to patients with mild to moderate hypertension. The purpose of the study was to investigate the antihypertensive action ofExpand
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Inhibition of cholinesterase activity after postganglionic denervation of the rat vas deferens: evidence for prejunctional supersensitivity to acetylcholine.
The supersensitivity of the smooth muscle of the vas deferens which occurs to norepinephrine after postganglionic denervation is believed to be due to a combination of prejunctional (loss of neuronalExpand
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Effects of anticholinesterase insecticides on hepatic microsomal metabolism.
Parathion, paraoxon, malathion, disulfoton and carbaryl, but not octamethyl pyrophos-phoramide, prolonged hexobarbital sleeping time in the mouse. The increase in sleeping time was apparently not dueExpand
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Pharmacological control of asthma.
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Specific subsensitivity of the rat atrium to cholinergic drugs.
The sensitivity of the atrium to drugs was studied subsequent to the subacute administration of the cholinesterase inhibitor O, O-diethyl S-2-(ethylthio) ethyl phosphorodithioate (Di-Syston) to rats.Expand
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