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droloxifene

Known as: (E)--1-[4'-(2-dimethylaminoethyoxy)phenyl]-1(3-hydroxyphenyl)-2-phenyl-but-1-ene, (E)-3-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol, 3-hydroxytamoxifen 
A phenolic analogue of tamoxifen, a nonsteroidal selective estrogen receptor modulator (SERM). Droloxifene competitively inhibits the binding of… Expand
National Institutes of Health

Papers overview

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Highly Cited
2003
Highly Cited
2003
A series of ferrocene derivatives based upon the structure of the antiestrogenic drug tamoxifen or of its active metabolite… Expand
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2001
2001
Although increased levels of C-reactive protein have been linked to E therapy, the significance of this finding and whether it… Expand
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2001
2001
Human papillomavirus (HPV) type 16 infects the genital tract and is generally acknowledged to be a causative agent of cervical… Expand
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Review
2000
Review
2000
Since the description of the first antioestrogen, MER 25, more than four decades ago (Lerner et al. 1958), and of tamoxifen ten… Expand
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Highly Cited
1999
Highly Cited
1999
We used mouse hepatoma (Hepa1c1c7) cells to study the role of the serine/threonine kinase Akt in the induction of GLUT1 gene… Expand
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1999
1999
Earlier study suggested that 3,4-dihydroxytamoxifen (tam catechol), a tamoxifen metabolite, is proximate to the reactive… Expand
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1998
1998
The identification and characterization of estrogen regulated genes in reproductive tissues is an important step in understanding… Expand
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Highly Cited
1997
Highly Cited
1997
PURPOSE Overexpression of the HER-2/c-neu/c-erbB2 proto-oncogene is associated with a worse prognosis in patients with breast… Expand
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1989
1989
The effects of tamoxifen, three of its in vivo metabolites and 3-hydroxytamoxifen on cellular proliferation and the induction of… Expand
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Highly Cited
1982
Highly Cited
1982
Abstract In the rat uterus, trans -tamoxifen (ICI-47,699, 1-[4-(2-dimethylaminoethoxy)phenyl]-1,2-diphenylbut-1( E )-ene) is a… Expand
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