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Tamoxifen

Known as: Tamoxifeno, TAM, (Z)-2-[4(1,2-diphenyl-1-butenyl)-phenoxyl]-N,N-dimethylethanamine 
An antineoplastic nonsteroidal selective estrogen receptor modulator (SERM). Tamoxifen competitively inhibits the binding of estradiol to estrogen… 
National Institutes of Health

Related topics

Related topics

50 relations

Narrower (28)

4-hydroxy-N-desmethyltamoxifen4-hydroxyospemifene4-hydroxytoremifeneH 1285

Broader (1)

Amines
Cyclophosphamide/Fluorouracil/TamoxifenIn BloodNCIt Antineoplastic Agent TerminologyPancreatic Neoplasm

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal women with node-positive, oestrogen-receptor-positive breast cancer on chemotherapy: a retrospective analysis…
Review
2006
Review
2006
The occurrence of selected pharmaceuticals in wastewater effluent and surface waters of the lower Tyne catchment.
Review
2006
Review
2006
Adherence to tamoxifen over the five-year course
SummaryPurposeTo estimate the proportion of older women who fail to complete 5 years of tamoxifen therapy and to identify… 
Highly Cited
2003
Highly Cited
2003
Meta-analysis of vascular and neoplastic events associated with tamoxifen
OBJECTIVE: Tamoxifen reduces the risk of developing breast cancer but also affects the risks of certain vascular and neoplastic… 
Highly Cited
2002
Highly Cited
2002
Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse.
In recent years, the Cre integrase from bacteriophage P1 has become an essential tool for conditional gene activation and/or… 
Review
2001
Review
2001
Mechanisms of tamoxifen-induced apoptosis
Tamoxifen (TAM) has been used in the treatment of breast cancer for over a decade. The observed clinical efficacy of TAM has been… 
Highly Cited
2001
Highly Cited
2001
Wave propagation in media having negative permittivity and permeability.
Wave propagation in a double negative (DNG) medium, i.e., a medium having negative permittivity and negative permeability, is… 
Review
1999
Review
1999
Weighing the risks and benefits of tamoxifen treatment for preventing breast cancer.
BACKGROUND In response to findings from the Breast Cancer Prevention Trial that tamoxifen treatment produced a 49% reduction in… 
Review
1991
Review
1991
The ovariectomized rat model of postmenopausal bone loss.
Review
1988
Review
1988
Effects of adjuvant tamoxifen and of cytotoxic therapy on mortality in early breast cancer. An overview of 61 randomized trials among 28,896 women
We sought information worldwide on mortality according to assigned treatment in all randomized trials that began before 1985 of… 
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