Estrogen Antagonists

Known as: Antiestrogens, estrogen blocker, Estrogen--Antagonists 
A substance that keeps cells from making or using estrogen (a hormone that plays a role in female sex characteristics, the menstrual cycle, and… (More)

Topic mentions per year

Topic mentions per year

1951-2018
05010015019512017

Papers overview

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Highly Cited
2009
Highly Cited
2009
PURPOSE Cross-talk between human epidermal growth factor receptors and hormone receptor pathways may cause endocrine resistance… (More)
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Highly Cited
2002
Highly Cited
2002
Selective estrogen receptor modulators (SERMs) mimic estrogen action in certain tissues while opposing it in others. The… (More)
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Highly Cited
2001
Highly Cited
2001
Estrogen receptors (ERs) mediate most of the biological effects of estrogen in mammary and uterine epithelial cells by binding to… (More)
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Highly Cited
2001
Highly Cited
2001
Trans-3,4',5-trihydroxystilbene (resveratrol), a phytoalexin present in grapes and grape products such as wine, has been… (More)
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Highly Cited
1998
Highly Cited
1998
The rat, mouse and human estrogen receptor (ER) exists as two subtypes, ER alpha and ER beta, which differ in the C-terminal… (More)
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Highly Cited
1997
Highly Cited
1997
Mixed antiestrogens, such as 4-hydroxytamoxifen (4HT), act as either partial agonists or antagonists of estrogen receptor (ER… (More)
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Highly Cited
1995
Highly Cited
1995
The phosphorylation of the human estrogen receptor (ER) serine residue at position 118 is required for full activity of the ER… (More)
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Highly Cited
1995
Highly Cited
1995
We have developed a series of in vitro models with which to evaluate the biological activity of estrogen receptor (ER) agonists… (More)
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Highly Cited
1992
Highly Cited
1992
BACKGROUND AND METHODS Tamoxifen, a synthetic antiestrogen, increases disease-free and overall survival when used as adjuvant… (More)
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Highly Cited
1978
Highly Cited
1978
Estrogen antagonists are widely used in the treatment of breast cancer, and studies of their mechanism of action may provide… (More)
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