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Estrogen Antagonists

Known as: Antiestrogens, estrogen blocker, Estrogen--Antagonists 
A substance that keeps cells from making or using estrogen (a hormone that plays a role in female sex characteristics, the menstrual cycle, and… 
National Institutes of Health

Related topics

Related topics

40 relations
AndrogensAntineoplastic AgentsAromatase InhibitorsEstrogen Receptor Modulators

Narrower (27)

CentchromanClomipheneDanazolEM 800

Broader (2)

Hormone AntagonistsPharmaceutical Preparations

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Development and characterization of a cell line that stably expresses an estrogen-responsive luciferase reporter for the detection of estrogen receptor agonist and antagonists.
Recently several advisory committees (EDSTAC, ICCVAM) have recommended that stable estrogen-dependent gene expression assays be… 
Highly Cited
2001
Highly Cited
2001
Use of an aromatase inhibitor for induction of ovulation in patients with an inadequate response to clomiphene citrate.
Highly Cited
1999
Highly Cited
1999
Coactivator peptides have a differential stabilizing effect on the binding of estrogens and antiestrogens with the estrogen receptor.
The effectiveness of estrogens in stimulating gene transcription mediated by the estrogen receptor (ER) appears to depend on ER… 
Highly Cited
1998
Highly Cited
1998
Activation of the Src/p21ras/Erk pathway by progesterone receptor via cross‐talk with estrogen receptor
The molecular mechanisms by which ovarian hormones stimulate growth of breast tumors are unclear. It has been reported previously… 
Highly Cited
1996
Highly Cited
1996
Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: the role of autophagy.
Active cell death in hormone-dependent cells was studied using cultured human mammary carcinoma cells (MCF-7) treated with the… 
Highly Cited
1995
Highly Cited
1995
Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor.
A conserved region in the hormone‐dependent activation domain AF2 of nuclear receptors plays an important role in transcriptional… 
Highly Cited
1994
Highly Cited
1994
Estrogen receptor-associated proteins: possible mediators of hormone-induced transcription.
The estrogen receptor is a transcription factor which, when bound to estradiol, binds DNA and regulates expression of estrogen… 
Highly Cited
1992
Highly Cited
1992
Estrogen-dependent, tamoxifen-resistant tumorigenic growth of MCF-7 cells transfected with HER2/neu
SummarySince the poor prognosis associated with HER2 amplified breast cancers might be explained by a mechanistic association… 
Highly Cited
1976
Highly Cited
1976
Characterization of the inappropriate gonadotropin secretion in polycystic ovary syndrome.
To evaluate gonadotropin release in polycystic ovary syndrome (PCO), one or more of the following hypothalamic-pituitary function… 
Review
1975
Review
1975
The formation of estrogens by central neuroendocrine tissues.
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