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Estrogen Antagonists

Known as: Antiestrogens, estrogen blocker, Estrogen--Antagonists 
A substance that keeps cells from making or using estrogen (a hormone that plays a role in female sex characteristics, the menstrual cycle, and… Expand
National Institutes of Health

Related topics

Related topics

40 relations
AndrogensAntineoplastic AgentsAromatase InhibitorsEstrogen Receptor Modulators
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Narrower (27)

CentchromanClomipheneDanazolEM 800
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Broader (2)

Hormone AntagonistsPharmaceutical Preparations

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Estrogen Receptor-Positive Breast Cancer: Exploiting Signaling Pathways Implicated in Endocrine Resistance.
Advancements in molecular profiling and endocrine therapy (ET) have led to more focused clinical attention on precision medicine… Expand
Review
2018
Review
2018
The Effect of Flaxseed in Breast Cancer: A Literature Review
Breast cancer is one of the most common cancers and the second most responsible for cancer mortality worldwide. In 2014, in… Expand
Review
2018
Review
2018
Selective estrogen receptor modulators (SERMs) and selective estrogen receptor degraders (SERDs) in cancer treatment.
Breast cancer is the most frequently diagnosed cancer in women, with estrogen receptor positive (ER+) breast cancer making up… Expand
Review
2018
Review
2018
Phytoestrogens and breast cancer: In vitro anticancer activities of isoflavones, lignans, coumestans, stilbenes and their analogs and derivatives.
  • P. Basu, C. Maier
  • Biomedicine & pharmacotherapy = Biomedecine…
  • 2018
    • Corpus ID: 52844479
Breast cancer is one of the leading causes of cancer-related morbidity and mortality among women worldwide. Phytoestrogens, plant… Expand
Highly Cited
2005
Highly Cited
2005
Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells.
Although nonclassical estrogen actions initiated at the cell surface have been described in many tissues, the identities of the… Expand
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Highly Cited
1999
Highly Cited
1999
The Estrogen Receptor β-Isoform (ERβ) of the Human Estrogen Receptor Modulates ERα Transcriptional Activity and Is a Key Regulator of the Cellular Response to Estrogens and Antiestrogens1.
The human estrogen receptor alpha (ERalpha) and the recently identified ERbeta share a high degree of amino acid homology… Expand
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Highly Cited
1998
Highly Cited
1998
Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta.
The rat, mouse and human estrogen receptor (ER) exists as two subtypes, ER alpha and ER beta, which differ in the C-terminal… Expand
Highly Cited
1995
Highly Cited
1995
Activation of the Estrogen Receptor Through Phosphorylation by Mitogen-Activated Protein Kinase
The phosphorylation of the human estrogen receptor (ER) serine residue at position 118 is required for full activity of the ER… Expand
Highly Cited
1992
Highly Cited
1992
Effects of tamoxifen on bone mineral density in postmenopausal women with breast cancer.
BACKGROUND AND METHODS Tamoxifen, a synthetic antiestrogen, increases disease-free and overall survival when used as adjuvant… Expand
Highly Cited
1986
Highly Cited
1986
Phenol red in tissue culture media is a weak estrogen: implications concerning the study of estrogen-responsive cells in culture.
Although much attention has been paid to the removal of hormones from sera and to the development of serum-free media for studies… Expand
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