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Estrogen Antagonists

Known as: Antiestrogens, estrogen blocker, Estrogen--Antagonists 
A substance that keeps cells from making or using estrogen (a hormone that plays a role in female sex characteristics, the menstrual cycle, and… Expand
National Institutes of Health

Related topics

Related topics

40 relations
AndrogensAntineoplastic AgentsAromatase InhibitorsEstrogen Receptor Modulators
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Narrower (27)

CentchromanClomipheneDanazolEM 800
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Broader (2)

Hormone AntagonistsPharmaceutical Preparations

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells.
Although nonclassical estrogen actions initiated at the cell surface have been described in many tissues, the identities of the… Expand
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Highly Cited
1999
Highly Cited
1999
The estrogen receptor beta-isoform (ERbeta) of the human estrogen receptor modulates ERalpha transcriptional activity and is a key regulator of the cellular response to estrogens and antiestrogens.
The human estrogen receptor alpha (ERalpha) and the recently identified ERbeta share a high degree of amino acid homology… Expand
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Highly Cited
1998
Highly Cited
1998
Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta.
The rat, mouse and human estrogen receptor (ER) exists as two subtypes, ER alpha and ER beta, which differ in the C-terminal… Expand
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Highly Cited
1997
Highly Cited
1997
Differential ligand activation of estrogen receptors ERalpha and ERbeta at AP1 sites.
The transactivation properties of the two estrogen receptors, ERalpha and ERbeta, were examined with different ligands in the… Expand
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Highly Cited
1997
Highly Cited
1997
CDK-Independent Activation of Estrogen Receptor by Cyclin D1
Both cyclin D1 and estrogens have an essential role in regulating proliferation of breast epithelial cells. We show here a novel… Expand
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Highly Cited
1997
Highly Cited
1997
Cloning, chromosomal localization, and functional analysis of the murine estrogen receptor beta.
Estrogen receptor beta (ER beta) is a novel steroid receptor that is expressed in rat prostate and ovary. We have cloned the… Expand
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Highly Cited
1995
Highly Cited
1995
Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase.
The phosphorylation of the human estrogen receptor (ER) serine residue at position 118 is required for full activity of the ER… Expand
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Highly Cited
1995
Highly Cited
1995
Tamoxifen activation of the estrogen receptor/AP-1 pathway: potential origin for the cell-specific estrogen-like effects of antiestrogens.
We find that tamoxifen is a potent activator of estrogen receptor (ER)- mediated induction of promoters regulated by AP-1 sites… Expand
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Highly Cited
1995
Highly Cited
1995
Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor.
A conserved region in the hormone-dependent activation domain AF2 of nuclear receptors plays an important role in transcriptional… Expand
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Highly Cited
1986
Highly Cited
1986
Phenol red in tissue culture media is a weak estrogen: implications concerning the study of estrogen-responsive cells in culture.
Although much attention has been paid to the removal of hormones from sera and to the development of serum-free media for studies… Expand
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