Estrogen Receptor Modulators

Known as: Modulators, Estrogen Receptor, Receptor Modulators, Estrogen, Modulator, Estrogen Receptor 
Substances that possess antiestrogenic actions but can also produce estrogenic effects as well. They act as complete or partial agonist or as… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Tamoxifen has been the most important therapeutic agent for the treatment of estrogen receptor (ER)-positive breast cancer for… (More)
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Highly Cited
2006
Highly Cited
2006
The status of the 66-kDa human estrogen receptor-alpha (hER-alpha66) is a critical determinant in the assessment of the prognosis… (More)
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Review
2004
Review
2004
Ligands for the nuclear receptor superfamily control many aspects of biology, including development, reproduction, and… (More)
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Highly Cited
2004
Highly Cited
2004
Obesity, from declining estrogen levels after menopause, increases the risk of heart disease, diabetes, and hypertension… (More)
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Review
2003
Review
2003
Antiestrogens include agents such as tamoxifen, toremifene, raloxifene, and fulvestrant. Currently, tamoxifen is the only drug… (More)
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Highly Cited
1999
Highly Cited
1999
Estrogen receptors (ERs alpha and beta) enhance transcription in response to estrogens by binding to estrogen response elements… (More)
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Review
1996
Review
1996
Estrogens regulate the growth, differentiation, and functioning of diverse target tissues, both within and outside of the… (More)
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Highly Cited
1996
Highly Cited
1996
The expression and stability of the estrogen receptor (ER) is the result of a complex process that is modulated by estrogens and… (More)
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Highly Cited
1993
Highly Cited
1993
The mouse estrogen receptor was shown to be constantly shuttling between the nucleus and cytoplasm although under steady-state… (More)
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Highly Cited
1993
Highly Cited
1993
We have shown previously that exposure of rat uterine cells in primary culture to estradiol (E2), insulin-like growth factor-I… (More)
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