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Crystal and molecular structure of paclitaxel (taxol).
The crystal structure of paclitaxel is determined to identify its conformational preferences that may be related to biological activity and analysis of the hydrogen-bonding network together with structure-activity studies may suggest which atoms of pac litaxel are important for binding to microtubule receptors. Expand
[Leu5]enkephalin: four cocrystallizing conformers with extended backbones that form an antiparallel β-sheet
[LeuS]enkephalin (Tyr-Gly-Gly-Phe-Leu) grown from N,N-dimethylformamide(DMFA)/water crystallizes with four quite different conformers side-by-side in the asymmetric unit. The four conformers withExpand
Photodimer of Thymine in Ultraviolet-Irradiated DNA: Proof of Structure by X-ray Diffraction
The structure of the thymine dimer in irradiated DNA is proved by single-crystal x-ray diffraction of the cis 5,5 : 6,6 isomer. Expand
Molecular design to mimic the copper(II) transport site of human albumin. The crystal and molecular structure of copper(II) – glycylglycyl-L-histidine-N-methyl amide monoaquo complex
Glycylglycyl-L-histidine-N-methyl amide is a copper-binding tripeptide designed and synthesized to mimic the copper-transport site of human albumin. Reddish-purple crystals of the copper-tripeptideExpand
Azidothymidine: crystal structure and possible functional role of the azido group.
Comparing the crystal and molecular structures of the anti-acquired immunodeficiency syndrome agent 3'-azido-3'-deoxythymidine with a hydrated thymidylate structure indicate that the azido group does not significantly affect the gross conformational preference of the molecule. Expand
Thyroid hormone stereochemistry. I. The molecular structures of 3,5,3'-triiodo-l-thyronine (T3) and l-thyroxine (T4)
found in several anhydrous borates. In the present structure the pentaborate rings have two relatively short boron-oxygen edges, with boron-oxygen bond lengths of 1.336 A [B(4)-O(4)] and 1.341 .&Expand
The crystal and molecular structure of perylene
Crystals of perylene, C20H12, are monoclinic with four molecules in a unit cell of dimensions a = 11.277, b = 10.826, c = 10.263Å, B = 100.55°, space group P21/a The intensities of 1135 reflexionsExpand
Ethylphenacemide and phenacemide: conformational similarities to diphenylhydantoin and stereochemical basis of anticonvulsant activity.
The three-dimensional molecular structures of the potent anticonvulsant agents phenacemide and ethylphenacemides have been determined by single-crystal x-ray diffraction, finding that in the crystalline state both molecules adopt a pseudocyclic conformation of the acetylurea chain through amide...carbonyl oxygen intramolecular hydrogen bonding. Expand