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Danazol

Known as: 1-Ethynyl-2,3,3a,3b,4,5,10,10a,10b,11,12,12a-dodecahydro-10a,12a-dimethyl-1H-cyclopental[7,8]phenanthro[3,2-d]isoxazol-1-ol, DAN, (17alpha)-Pregna-2,4-dien-20-yno[2,3-d]isoxazol-17-ol 
A synthetic androgen derived from ethinyl testosterone. Danazol indirectly reduces estrogen production by decreasing pituitary secretion of follicle… 
National Institutes of Health

Related topics

Related topics

34 relations

Narrower (7)

21-chlorodanazolAzolBonzolDanocrine
AndrostanesBreast Fibrocystic DiseaseDanazol:PrThr:Pt:Urine:Ord:ScreenDisorders of Porphyrin Metabolism

Broader (1)

Estrogen Antagonists

Papers overview

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1990
1990
Danazol. A synthetic steroid with diverse biologic effects.
: Danocrine (danazol) is a synthetic steroid with multiple and diverse biologic effects. It exerts these effects by binding to… 
Highly Cited
1982
Highly Cited
1982
Systemic lupus erythematosus: two patients treated with danazol
Two women with systemic lupus erythematosus who showed premenstrual flaring of the disease were treated with danazol, which… 
1979
1979
Hormonal, metabolic and clinical effects of danazol in the treatment of endometriosis.
The effect of danazol in a dose of 600 mg a day was studied in 20 women with moderate or severe endometriosis. The clinical… 
1979
1979
Danazol and the premenstrual syndrome.
Danazol as a powerful antigonadotrophin is a logical mode of treatment for patients with premenstrual symptoms. Its preliminary… 
1979
1979
Effects of Danazol on Gonadotropin Levels in Castrated Rhesus Monkeys
Danazol is widely used in the management of endometriosis and mammary dysplasia. However, its mechanism of action is still… 
1977
1977
Endocrine effects of danazol in menstruating women.
14 healthy women (20-35 years of age) with regular menses were given danazol a drug with antigonadotrophic activity in order to… 
1977
1977
Pharmacology of danazol.
: We have established that danazol is an orally active pituitary gonadotrophin inhibitory agent devoid of oestrogenic and… 
1976
1976
The structure and function of acid proteases. VI. Effects of acid protease-specific inhibitors on the acid proteases from Aspergillus niger var. macrosporus.
1. The Type B acid protease from Aspergillus niger var. macrosporus was inactivated by reaction with diazoacetyl-DL-norleucine… 
1976
1976
Contraceptive properties of Danazol.
The contraceptive properties of Danazol a steroid derivative of eth isterone were investigated in 30 volunteers. The drug was… 
1975
1975
The effects of danazol on gonadotropins and steroid blood levels in normal and anovulatory women.
: The effect of Danazol, a new gonadotropin inhibitor, was examined in four categories of patients. (1) Ten normal women…