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Androstanes

Known as: Androstanes [Chemical/Ingredient], androstane, androstane compound 
The family of steroids from which the androgens are derived.
National Institutes of Health

Papers overview

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Highly Cited
2007
Review
2005
Review
2005
Drug metabolizing enzymes (DMEs) play central roles in the metabolism, elimination and detoxification of xenobiotics and drugs… 
Highly Cited
2003
Highly Cited
2003
Bilirubin clearance is one of the numerous important functions of the liver. Defects in this process result in jaundice, which is… 
Highly Cited
2003
Highly Cited
2003
Through a multiplex promoter spanning 218 kb, the phase II UDP-glucuronosyltransferase 1A (UGT1) gene encodes at least eight… 
Highly Cited
2003
Highly Cited
2003
The orphan nuclear constitutive androstane receptor (CAR) is proposed to play a central role in the response to xenochemical… 
Highly Cited
2002
Highly Cited
2002
The multidrug resistance-associated protein 2 (MRP2, ABCC2), mediates the efflux of several conjugated compounds across the… 
Highly Cited
2002
Highly Cited
2002
The nuclear pregnane X receptor (PXR) and constitutive androstane receptor (CAR) play central roles in protecting the body… 
Highly Cited
2000
Highly Cited
2000
Xenobiotics induce the transcription of cytochromes P450 (CYPs) 2B and 3A through the constitutive androstane receptor (CAR… 
Highly Cited
1998
Highly Cited
1998
The orphan receptor CAR-β (ref. 1) binds DNA as a heterodimer with the retinoid-X receptor and activates gene transcription in a…