Androstanes

Known as: Androstanes [Chemical/Ingredient], androstane, androstane compound 
The family of steroids from which the androgens are derived.
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
Hepatocellular carcinoma (HCC) is known to progress through a step often called tumor promotion. Phenobarbital (PB) is the… (More)
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Highly Cited
2003
Highly Cited
2003
Through a multiplex promoter spanning 218 kb, the phase II UDP-glucuronosyltransferase 1A (UGT1) gene encodes at least eight… (More)
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Highly Cited
2003
Highly Cited
2003
Bilirubin clearance is one of the numerous important functions of the liver. Defects in this process result in jaundice, which is… (More)
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Highly Cited
2003
Highly Cited
2003
The orphan nuclear constitutive androstane receptor (CAR) is proposed to play a central role in the response to xenochemical… (More)
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Highly Cited
2002
Highly Cited
2002
The multidrug resistance-associated protein 2 (MRP2, ABCC2), mediates the efflux of several conjugated compounds across the… (More)
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Highly Cited
2002
Highly Cited
2002
The nuclear pregnane X receptor (PXR) and constitutive androstane receptor (CAR) play central roles in protecting the body… (More)
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Highly Cited
2002
Highly Cited
2002
The NR1I subfamily of nuclear receptors contains a phylogenetically diverse array of receptors related to the mammalian pregnane… (More)
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Highly Cited
2000
Highly Cited
2000
Xenobiotics induce the transcription of cytochromes P450 (CYPs) 2B and 3A through the constitutive androstane receptor (CAR… (More)
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Highly Cited
2000
Highly Cited
2000
The barbiturate phenobarbital induces the transcription of cytochromes P450 (CYPs) 2B through the constitutive androstane… (More)
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Highly Cited
1998
Highly Cited
1998
The orphan receptor CAR-β (ref. 1) binds DNA as a heterodimer with the retinoid-X receptor and activates gene transcription in a… (More)
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