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Aromatase Inhibitors
Known as:
Androstenedione Aromatase Inhibitor
, Estrogen Synthase Inhibitor
, Estrogen Synthetase Inhibitor
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Any substance that inhibits aromatase, an enzyme responsible for the conversion of cholesterol to pregnenolone and the peripheral aromatization of…
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National Institutes of Health
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Related topics
Related topics
15 relations
Narrower (9)
Aminoglutethimide
Fadrozole
anastrozole
exemestane
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Broader (1)
Enzyme Inhibitors
Estrogen Antagonists
In Blood
aspects of radiation effects
chemical synthesis
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Use of endocrine therapy following diagnosis of ductal carcinoma in situ or early invasive breast cancer
B. Virnig
,
M. Torchia
,
Stephanie L. Jarosek
,
Sara B. Durham
,
T. Tuttle
2012
Corpus ID: 68396035
Review
2008
Review
2008
Prospects of neoadjuvant aromatase inhibitor therapy in breast cancer
J. Dixon
Expert Review of Anticancer Therapy
2008
Corpus ID: 32240835
Over 40% of breast cancer patients are older than 70 years of age. In the last three decades, several clinical trials have…
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2007
2007
EVALUATION OF LETROZOLE THERAPEUTIC EFFECT IN INFERTILE WOMEN
F. A. Asbagh
,
O. Azmodeh
,
+5 authors
N. Salsabili
2007
Corpus ID: 74349752
Combination therapy with clomiphene citrate plus gonadotropin (clomiphene citrate plus HMG) in induction ovulation reduce the…
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Review
2001
Review
2001
Role of anti-aromatase agents in postmenopausal advanced breast cancer
R. Murray
Cancer Chemotherapy and Pharmacology
2001
Corpus ID: 34707699
Abstract.Purpose: Endocrine therapy is a well-recognized approach to the treatment of postmenopausal patients with advanced…
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2000
2000
Survival in patients with metastatic breast cancer: analysis of randomized studies comparing oral aromatase inhibitors versus megestrol
A. Messori
,
F. Cattel
,
S. Trippoli
,
M. Vaiani
Anti-Cancer Drugs
2000
Corpus ID: 44563316
In patients with metastatic breast cancer, second-line therapy with aromatase inhibitors can improve survival in comparison with…
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1998
1998
New Aromatase Inhibitors
T. Volm
,
V. Möbus
,
R. Kreienberg
Oncology Research and Treatment
1998
Corpus ID: 71643168
Tamoxifen still is the mainstay of endocrine therapy in women with advanced breast cancer. Response rates in hormone receptor…
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1997
1997
Effects of aromatase inhibitors on reproduction in male three-spined sticklebacks, Gasterosteus aculeatus, exposed to long and short photoperiods
Cecilia Bornestaf
,
E. Antonopoulou
,
Ian Mayer
,
B. Borg
Fish Physiology & Biochemistry
1997
Corpus ID: 24159656
Three-spined stickleback Gasterosteus aculeatus, males were implanted with Silastic capsules filled with different aromatase…
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Review
1988
Review
1988
Aromatase inhibitors as new endocrine therapy for breast cancer.
Angela M. H. Brodie
,
M. Dowsett
,
R. Coombes
Cancer treatment and research
1988
Corpus ID: 267055
The role of estrogen in promoting the growth of hormone-dependent mammary tumors is well established. Inhibition of estrogen…
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1984
1984
Synthesis and evaluation of 19-aza- and 19-aminoandrostenedione analogues as potential aromatase inhibitors.
J. Lovett
,
M. Darby
,
R. Counsell
Journal of Medicinal Chemistry
1984
Corpus ID: 19960992
Derivatives of 19- azaandrostenedione (10 beta-amino-4- estrene -3,17-dione, 2) and 19-amino-4-androstene-3,17-dione (3) were…
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1983
1983
The role of aromatase inhibitors in breast cancer.
T. Powles
Seminars in Oncology
1983
Corpus ID: 25054139
Aminoglutethimide (AG) has antitumor activity in disseminated breast cancer similar to that of surgical adrenalectomy. AG works…
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