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Aromatase Inhibitors

Known as: Androstenedione Aromatase Inhibitor, Estrogen Synthase Inhibitor, Estrogen Synthetase Inhibitor 
Any substance that inhibits aromatase, an enzyme responsible for the conversion of cholesterol to pregnenolone and the peripheral aromatization of… 
National Institutes of Health

Related topics

Related topics

15 relations

Narrower (9)

AminoglutethimideFadrozoleanastrozoleexemestane

Broader (1)

Enzyme Inhibitors
Estrogen AntagonistsIn Bloodaspects of radiation effectschemical synthesis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Heterogeneous estrogen receptor expression in circulating tumor cells suggests diverse mechanisms of fulvestrant resistance
Highly Cited
2011
Highly Cited
2011
Synthesis and structureeactivity relationship of 1- and 2-substituted- 1,2,3-triazole letrozole-based analogues as aromatase inhibitors
A series of bisand mono-benzonitrile or phenyl analogues of letrozole 1, bearing (1,2,3 and 1,2,5)-triazole or imidazole, were… 
Highly Cited
2007
Highly Cited
2007
Region‐specific expression and sex‐steroidal regulation on aromatase and its mRNA in the male rat brain: Immunohistochemical and in situ hybridization analyses
The brain has an estrogen‐biosynthetic potential resulting from the presence of neuronal aromatase, which controls the… 
Review
2006
Review
2006
Fulvestrant ('Faslodex'): current and future role in breast cancer management.
2004
2004
Giving patients a choice improves quality of life: a multi-centre, investigator-blind, randomised, crossover study comparing letrozole with anastrozole.
Review
2003
Review
2003
Role of steroid sulfatase in local formation of estrogen in post-menopausal breast cancer patients
2003
2003
Forebrain Fos responses to reproductively related chemosensory cues in aromatase knockout mice
Review
2002
Review
2002
Aromatase inhibitors in breast cancer: an update.
BACKGROUND Tamoxifen has been the endocrine treatment of choice for patients with breast cancer. The development of selective… 
2000
2000
[Aromatase inhibitors in the treatment of breast cancer].
La disponibilite sur le marche de plusieurs inhibiteurs de l'aromatase de troisieme generation, qu'il s'agisse de l'exemestane… 
1999
1999
Anastrozole shows evidence of activity in postmenopausal patients who have responded or stabilised on formestane therapy.
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