• Publications
  • Influence
Pregnancies after intracytoplasmic injection of single spermatozoon into an oocyte
Intracytoplasmic sperm injection is used to treat couples with infertility because of severely impaired sperm characteristics, and in whom IVF and SUZI had failed. Expand
Detection of sperm in men with Y chromosome microdeletions of the AZFa, AZFb and AZFc regions.
Microdeletion of the entire AZFa or AZFb regions of the Y chromosome portends an exceptionally poor prognosis for sperm retrieval, whereas the majority of men with AZFc deletion have sperm within the semen or testes available for use in IVF/ICSI. Expand
Fertilization and pregnancy outcome with intracytoplasmic sperm injection for azoospermic men.
In cases of obstructive azoospermia, fertilization and pregnancy rates with epididymal spermatozoa were higher than those achieved using spermatozosa obtained from the testes of men with non-obstructive azonpermia. Expand
Successful fertility treatment for Klinefelter's syndrome.
Microdissection testicular sperm extraction is an effective sperm retrieval technique in men with Klinefelter's syndrome and men with hypogonadism who respond to medical therapy may have a better chance of sperm retrieval. Expand
Oolemma characteristics in relation to survival and fertilization patterns of oocytes treated by intracytoplasmic sperm injection.
The aim of this study was to analyse the various reactions displayed by the oolemma to the penetrating pipette during intracytoplasmic sperm injection (ICSI) and correlate them with clinical factors,Expand
Success of testicular sperm injection and intracytoplasmic sperm injection in men with klinefelter syndrome
The sperm retrieval rate was 72% (39 of 54) per TESE attempt, and 29 of the 42 different men (69%) had adequate sperm found for ICSI, and the mean testosterone level rose to 17.0 nmol/liter (P < 0.01). Expand
Success of testicular sperm extraction [corrected] and intracytoplasmic sperm injection in men with Klinefelter syndrome.
Sperm retrieval and ICSI success in men with Klinefelter syndrome are comparable with other men with nonobstructive azoospermia treated at the authors' center, and TESE/ICSI is a successful intervention for the majority of patients. Expand
Intracytoplasmic sperm injection: a novel treatment for all forms of male factor infertility.
Intracytoplasmic sperm injection can be used successfully to treat couples who have failed IVF or who have too few spermatozoa for conventional methods of in vitro insemination, and sperm parameters do not clearly affect the outcome of this technique. Expand
AZFb deletions predict the absence of spermatozoa with testicular sperm extraction: preliminary report of a prognostic genetic test.
Results suggest that the presence of an AZFb deletion is a significantly adverse prognostic finding for TESE, and Alternatives such as donor insemination or adoption should be considered or therapy delayed until improved results with round spermatid injections are likely. Expand
Human zona pellucida micromanipulation and monozygotic twinning frequency after IVF.
This investigation is the largest to date describing the relationship between MZ twins and zona procedures, and studies with even greater statistical power are needed to clarify it more precisely, particularly in DER and FET settings. Expand