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anastrozole

Known as: Anastrozol, 1,3-Benzenediacetonitrile, alpha,alpha,alpha',alpha'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-, anastrozole [Chemical/Ingredient] 
A nonsteroidal inhibitor of estrogen synthesis that resembles paclitaxel in chemical structure. As a third-generation aromatase inhibitor… 
National Institutes of Health

Related topics

Related topics

12 relations

Broader (4)

Antineoplastic Agents, HormonalAromatase InhibitorsNitrilesTriazoles

Narrower (3)

ArimidexZD-1033anastrozole 1 MG Oral Tablet [Arimidex]
Drug AllergyMammary NeoplasmsNCIt Antineoplastic Agent TerminologyPregnancy

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2006
Review
2006
What do we know about the mechanisms of aromatase inhibitor resistance?
Review
2006
Review
2006
Fulvestrant ('Faslodex'): current and future role in breast cancer management.
2005
2005
Model systems: Mechanisms involved in the loss of sensitivity to letrozole
Highly Cited
2003
Highly Cited
2003
The ATAC ('Arimidex', Tamoxifen, Alone or in Combination) Trial in Postmenopausal Women with Early Breast Cancer – Updated Efficacy Results Based on a Median Follow-up of 47 Months
Review
2003
Review
2003
Role of steroid sulfatase in local formation of estrogen in post-menopausal breast cancer patients
2002
2002
Aromatase inhibitors in breast cancer
Highly Cited
2001
Highly Cited
2001
Biological and clinical effects of aromatase inhibitors in neoadjuvant therapy
Highly Cited
2001
Highly Cited
2001
Aromatization mediates testosterone's short-term feedback restraint of 24-hour endogenously driven and acute exogenous gonadotropin-releasing hormone-stimulated luteinizing hormone and follicle…
The present clinical study examines the neuroregulatory hypothesis that feedback restraint of LH and FSH secretion by… 
Highly Cited
2001
Highly Cited
2001
Analysis of cross-resistance of the selective estrogen receptor modulators arzoxifene (LY353381) and LY117018 in tamoxifen-stimulated breast cancer xenografts.
PURPOSE Cross-resistance is the primary issue facing the evaluation of new antiestrogens to treat metastatic breast cancer… 
Highly Cited
1961
Highly Cited
1961
The effect of total and subtotal adrenalectomy on the renal and extra-renal response of the domestic duct (Anas platyrhynchus) to saline loading.
Total adrenalectomy of the saline loaded domestic duck resulted in complete obliteration of the extra-renal excretory response… 
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