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desacetylcefotaxime

Known as: deacetylcefotaxime 
 
National Institutes of Health

Papers overview

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Highly Cited
2003
Highly Cited
2003
Clostridium difficile is recognized as an important nosocomial pathogen. C. difficile infection (CDI) is thought to arise as a… Expand
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Highly Cited
1993
Highly Cited
1993
MICs of six oral cephalosporins (cefdinir, cefpodoxime, cefaclor, cefuroxime, cefixime and Ro 40-6890), four quinolones… Expand
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Highly Cited
1993
Highly Cited
1993
Cefotaxime and ceftriaxone have proven to be effective in pyogenic infections of the central nervous system. Since in some… Expand
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1991
1991
Since clinical trials comparing the efficacies of different antibiotic regimens for treatment of brain abscesses are difficult to… Expand
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1987
1987
Eighty-seven organisms were tested against ceftriaxone, cefotaxime, desacetylcefotaxime, and the combination of cefotaxime and… Expand
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Highly Cited
1985
Highly Cited
1985
The pharmacokinetics and cerebrospinal fluid (CSF) penetration of cefotaxime (Ctx) and desacetylcefotaxime (dCtx) were evaluated… Expand
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1984
1984
: Although the antibacterial activity of desacetylcefotaxime (des-CTX), the principal metabolite of cefotaxime (CTX), is… Expand
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Highly Cited
1982
Highly Cited
1982
  • H. Neu
  • Reviews of infectious diseases
  • 1982
  • Corpus ID: 7814579
Cefotaxime is metabolized to 3-desacetylcefotaxime. The antibacterial activity of desacetylcefotaxime is four- to eightfold less… Expand
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Highly Cited
1982
Highly Cited
1982
The level of antimicrobial activity of 3-desacetylcefotaxime was found to be approximately eightfold lower than that of… Expand
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Highly Cited
1980
Highly Cited
1980
 
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