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desacetylcefotaxime

Known as: deacetylcefotaxime 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

Cefotaxime
analogs & derivatives

Narrower (1)

desacetylcefotaxime, monosodium salt

Papers overview

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1998
1998
Clinical and pharmacological evaluation of a modified cefotaxime bid regimen versus traditional tid in pediatric lower respiratory tract infections.
Review
1990
Review
1990
Pathophysiologic basis for the use of third-generation cephalosporins.
1986
1986
Colorimetric detection and spectrophotometric determination of the aminothiazolyl-alkoxyimino beta-lactams.
The 2-aminothiazolyl-4-yl-2-alkoxyiminoacetamido substituent-containing beta-lactam antibiotics (cephalosporins and monobactams… 
1984
1984
Cefotaxime and desacetylcefotaxime: an example of advantageous antimicrobial metabolism.
: Although the antibacterial activity of desacetylcefotaxime (des-CTX), the principal metabolite of cefotaxime (CTX), is… 
1984
1984
In vitro synergy and potentiation between cefotaxime and desacetylcefotaxime against clinical isolates of Bacteroides.
A broth microdilution checkerboard system was used to determine the activity of cefotaxime (CTX) and desacetylcefotaxime (des-CTX… 
Highly Cited
1982
Highly Cited
1982
Antibacterial activity of desacetylcefotaxime alone and in combination with cefotaxime.
Cefotaxime is metabolized to 3-desacetylcefotaxime. The antibacterial activity of desacetylcefotaxime is four- to eightfold less… 
1982
1982
Metabolism of cefotaxime in animals and humans.
The metabolism of [14C]cefotaxime was studied in vivo in rats, dogs, and humans and in vitro in cells of rats and rabbits… 
1982
1982
Clinical pharmacokinetics of cefotaxime in patients with normal and reduced renal function.
Two analytic methods for measuring cefotaxime, microbiologic and high-pressure liquid chromatography (HPLC), were compared in… 
1981
1981
Comparison of the renal excretory mechanisms of cefmenoxime and other cephalosporins: effect of para-aminohippurate on renal clearance and intrarenal distribution of cephalosporins in rabbits.
The renal excretory mechanism of cefmenoxime in rabbits was compared with that of 6 other cephalosporins (cefotaxime… 
Highly Cited
1980
Highly Cited
1980
Metabolism of cefotaxime in animals and man.
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