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desacetylcefotaxime

Known as: deacetylcefotaxime 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

Cefotaxime
analogs & derivatives

Narrower (1)

desacetylcefotaxime, monosodium salt

Papers overview

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1994
1994
Alkaline hydrolysis of cefotaxime. A HPLC and 1H NMR study.
A kinetic study on the alkaline hydrolysis of cefotaxime at pH 10.5 and 37 degrees C has been carried out by using HPLC and 1H… 
Highly Cited
1993
Highly Cited
1993
Susceptibility of 170 penicillin-susceptible and penicillin-resistant pneumococci to six oral cephalosporins, four quinolones, desacetylcefotaxime, Ro 23-9424 and RP 67829.
MICs of six oral cephalosporins (cefdinir, cefpodoxime, cefaclor, cefuroxime, cefixime and Ro 40-6890), four quinolones… 
Review
1990
Review
1990
Pathophysiologic basis for the use of third-generation cephalosporins.
1989
1989
Antimicrobial activity of Ro 23-9424, a novel ester-linked codrug of fleroxacin and desacetylcefotaxime
Ro 23-9424 is a novel ester-linked codrug of fleroxacin (Ro 23-6240; AM-833) and the cefotaxime metabolite desacetylcefotaxime… 
1986
1986
Colorimetric detection and spectrophotometric determination of the aminothiazolyl-alkoxyimino beta-lactams.
The 2-aminothiazolyl-4-yl-2-alkoxyiminoacetamido substituent-containing beta-lactam antibiotics (cephalosporins and monobactams… 
1985
1985
Rapid chromatographic determination of cefotaxime and its metabolite in biological fluids.
1984
1984
Cefotaxime and desacetylcefotaxime: an example of advantageous antimicrobial metabolism.
: Although the antibacterial activity of desacetylcefotaxime (des-CTX), the principal metabolite of cefotaxime (CTX), is… 
1984
1984
In vitro synergy and potentiation between cefotaxime and desacetylcefotaxime against clinical isolates of Bacteroides.
A broth microdilution checkerboard system was used to determine the activity of cefotaxime (CTX) and desacetylcefotaxime (des-CTX… 
Highly Cited
1982
Highly Cited
1982
Antibacterial activity of desacetylcefotaxime alone and in combination with cefotaxime.
Cefotaxime is metabolized to 3-desacetylcefotaxime. The antibacterial activity of desacetylcefotaxime is four- to eightfold less… 
Highly Cited
1980
Highly Cited
1980
Metabolism of cefotaxime in animals and man.
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