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Cefotaxime

Known as: Cefotaxim, Céfotaxime, (6R,7R)-3-(Acetoxymethyl)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 
A third generation semisynthetic cephalosporin antibiotic with bactericidal activity. Cefotaxime inhibits mucopeptide synthesis by binding to and… 
National Institutes of Health

Related topics

Related topics

41 relations
Acinetobacter InfectionsBacterial InfectionsBone Diseases, InfectiousCefotaxime 1000 MG Injection

Broader (1)

Anti-Bacterial Agents

Narrower (10)

BiosintCefotaxime SodiumClaforanHR-756

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Antimicrobial resistance and ESBL prevalence in Pseudomonas aeruginosa strains isolated from clinical specimen by phenotypic and genotypic methods
1 رایداتسا یکشزپ یسانش بورکیم ، یلوکلوم يژولویب تاقیقحت زکرم ، هاگشناد یکشزپ مولع اللها هیقب ) جع ( ، ،نارهت ناریا 2… 
2007
2007
Genetic transformation of embryogenic cultures and recovery of transgenic plants in Vitis vinifera, Vitis rotundifolia and Vitis hybrids
Factors influencing Agrobacterium-mediated transformation of 15 Vitis rotundifolia, Vitis rupestris, Vitis vinifera and Vitis… 
1996
1996
Adult group B streptococcal disease.
1984
1984
Cefotaxime and desacetylcefotaxime: an example of advantageous antimicrobial metabolism.
: Although the antibacterial activity of desacetylcefotaxime (des-CTX), the principal metabolite of cefotaxime (CTX), is… 
Highly Cited
1982
Highly Cited
1982
Antibacterial activity of desacetylcefotaxime alone and in combination with cefotaxime.
Cefotaxime is metabolized to 3-desacetylcefotaxime. The antibacterial activity of desacetylcefotaxime is four- to eightfold less… 
1982
1982
Metabolism of cefotaxime in animals and humans.
The metabolism of [14C]cefotaxime was studied in vivo in rats, dogs, and humans and in vitro in cells of rats and rabbits… 
1982
1982
Clinical efficacy of cefotaxime in serious infections
Thirty-five patients underwent 38 treatment courses with cefotaxime. Documented infections included 11 bacteremias, 7 cases of… 
1981
1981
Assay of cefotaxime by high-pressure-liquid chromatography.
A high-pressure-liquid chromatographic (HPLC) procedure for quantitative assay of cefotaxime (CT) and its major metabolite in… 
1979
1979
The comparative beta-lactamase resistance and inhibitory activity of 1-oxa cephalosporin, cefoxitin and cefotaxime.
The beta-lactamase stability and inhibitory activity of 1-oxa cephalosporin, (6R,7R)-7-[[carboxy(4-hydroxyphenyl)acetyl]amino]-7… 
1979
1979
[Clinical experience with a new cephalosporin derivative, Cefotaxim].