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Cefotaxime

Known as: Cefotaxim, Céfotaxime, (6R,7R)-3-(Acetoxymethyl)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 
A third generation semisynthetic cephalosporin antibiotic with bactericidal activity. Cefotaxime inhibits mucopeptide synthesis by binding to and… 
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
ABSTRACT A Swedish patient of Indian origin traveled to New Delhi, India, and acquired a urinary tract infection caused by a… 
Review
2009
Review
2009
SUMMARY AmpC β-lactamases are clinically important cephalosporinases encoded on the chromosomes of many of the Enterobacteriaceae… 
Review
2004
Review
2004
The production of β-lactamases is the predominant cause of resistance to β-lactam antibiotics in gram-negative bacteria. These… 
Highly Cited
1999
Highly Cited
1999
BACKGROUND In patients with cirrhosis and spontaneous bacterial peritonitis, renal function frequently becomes impaired. This… 
Highly Cited
1994
Highly Cited
1994
DNA SHUFFLING is a method for in vitro homologous recombination of pools of selected mutant genes by random fragmentation and… 
Highly Cited
1988
Highly Cited
1988
Before 1985 at the Pitié-Salpêtrière Hospital in Paris (2,400 beds), resistance to cefotaxime in clinical isolates of… 
Review
1988
Review
1988
Ciprofloxacin is one of a new generation of fluorinated quinolones structurally related to nalidixic acid. The primary mechanism… 
Highly Cited
1983
Highly Cited
1983
SummaryIn conjugational crosses, threeKlebsiella pneumoniae strains and oneSerratia marcescens strain have been demonstrated to…