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Cefotaxime

Known as: Cefotaxim, Céfotaxime, (6R,7R)-3-(Acetoxymethyl)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 
A third generation semisynthetic cephalosporin antibiotic with bactericidal activity. Cefotaxime inhibits mucopeptide synthesis by binding to and… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
  • G. Kampf
  • Antibiotics
  • 2018
  • Corpus ID: 56169076
Biocidal agents used for disinfection are usually not suspected to enhance cross-resistance to antibiotics. The aim of this… Expand
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Highly Cited
2009
Highly Cited
2009
ABSTRACT A Swedish patient of Indian origin traveled to New Delhi, India, and acquired a urinary tract infection caused by a… Expand
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Review
2009
Review
2009
  • G. Jacoby
  • Clinical Microbiology Reviews
  • 2009
  • Corpus ID: 25382533
SUMMARY AmpC β-lactamases are clinically important cephalosporinases encoded on the chromosomes of many of the Enterobacteriaceae… Expand
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Highly Cited
2008
Highly Cited
2008
Concentrations of nine antibiotics [erythromycin-H(2)O (ERY-H(2)O); trimethoprim (TMP); tetracycline (TET); norfloxacin (NOR… Expand
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Highly Cited
2005
Highly Cited
2005
SummaryIn conjugational crosses, threeKlebsiella pneumoniae strains and oneSerratia marcescens strain have been demonstrated to… Expand
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Highly Cited
2004
Highly Cited
2004
Abstract122 multiple trauma patients staying in the ICU for 5 or more days and needing mechanical ventilation were investigated… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND In patients with cirrhosis and spontaneous bacterial peritonitis, renal function frequently becomes impaired. This… Expand
Highly Cited
1994
Highly Cited
1994
DNA SHUFFLING is a method for in vitro homologous recombination of pools of selected mutant genes by random fragmentation and… Expand
Highly Cited
1988
Highly Cited
1988
Before 1985 at the Pitié-Salpêtrière Hospital in Paris (2,400 beds), resistance to cefotaxime in clinical isolates of… Expand
Highly Cited
1985
Highly Cited
1985
We compared the effectiveness and incidence of nephrotoxicity of ampicillin‐tobramycin and cefotaxime in 73 cirrhotics who had… Expand