Cefotaxime

Known as: Cefotaxim, Céfotaxime, (6R,7R)-3-(Acetoxymethyl)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 
A third generation semisynthetic cephalosporin antibiotic with bactericidal activity. Cefotaxime inhibits mucopeptide synthesis by binding to and… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
A Swedish patient of Indian origin traveled to New Delhi, India, and acquired a urinary tract infection caused by a carbapenem… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Leptospirosis is an important cause of fever in the rural tropics. Since 1996, there has been a marked increase in the… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND The emergence of drug-resistant strains of bacteria has complicated treatment decisions and may lead to treatment… (More)
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Highly Cited
2000
Highly Cited
2000
To estimate the diversity of extended-spectrum beta-lactamases in Brazil, 18 strains from different species of the family… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND In patients with cirrhosis and spontaneous bacterial peritonitis, renal function frequently becomes impaired. This… (More)
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Highly Cited
1998
Highly Cited
1998
A group of cefotaxime-resistant Citrobacter freundii and Escherichia coli isolates were collected by a clinical laboratory in a… (More)
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Highly Cited
1994
Highly Cited
1994
DNA SHUFFLING is a method for in vitro homologous recombination of pools of selected mutant genes by random fragmentation and… (More)
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Highly Cited
1988
Highly Cited
1988
Before 1985 at the Pitié-Salpêtrière Hospital in Paris (2,400 beds), resistance to cefotaxime in clinical isolates of… (More)
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Highly Cited
1985
Highly Cited
1985
We compared the effectiveness and incidence of nephrotoxicity of ampicillin-tobramycin and cefotaxime in 73 cirrhotics who had… (More)
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Highly Cited
1983
Highly Cited
1983
In conjugational crosses, threeKlebsiella pneumoniae strains and oneSerratia marcescens strain have been demonstrated to transfer… (More)
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