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brinzolamide

Known as: (R)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno(3,2-e)-1,2-thiazine-6-sulfonamide, brinzolamide [Chemical/Ingredient] 
A sulfonamide and carbonic anhydrase inhibitor with specific affinity for carbonic anhydrase II. Following topical ocular administration… Expand
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Nanocrystal-based drug delivery systems provide important tools for ocular formulation development, especially when considering… Expand
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Highly Cited
2013
Highly Cited
2013
Carbonic anhydrases (CAs, EC 4.2.1.1) are metalloenzymes that catalyze the reversible hydration of carbon dioxide and bicarbonate… Expand
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Highly Cited
2009
Highly Cited
2009
PURPOSE To compare the diurnal and nocturnal effects of brinzolamide and timolol on intraocular pressure (IOP) in patients… Expand
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Highly Cited
2008
Highly Cited
2008
Aims: To assess the effects of brinzolamide and dorzolamide on ocular haemodynamics and retinal oxygen saturation in patients… Expand
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Highly Cited
2005
Highly Cited
2005
OBJECTIVE To estimate the intraocular pressure (IOP) reduction achieved by the most frequently prescribed glaucoma drugs and a… Expand
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Highly Cited
2005
Highly Cited
2005
The inhibition of a newly cloned human carbonic anhydrase (CA, EC 4.2.1.1), isozyme XII (hCA XII), has been investigated with a… Expand
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2001
2001
PURPOSE The aim was to compare topical brinzolamide 1% twice daily with dorzolamide 2% twice daily, each given with timolol 0.5… Expand
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2000
2000
Two independent, prospective, multicenter, double-masked, parallel group trials were conducted to compare the ocular comfort of… Expand
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2000
2000
BACKGROUND The first topically active carbonic anhydrase inhibitor, dorzolamide, was developed to circumvent the adverse systemic… Expand
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Review
2000
Review
2000
There was a time gap of over 40 years between the demonstrated oral effectiveness of acetazolamide in lowering the intraocular… Expand
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