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brinzolamide

Known as: (R)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno(3,2-e)-1,2-thiazine-6-sulfonamide, brinzolamide [Chemical/Ingredient] 
A sulfonamide and carbonic anhydrase inhibitor with specific affinity for carbonic anhydrase II. Following topical ocular administration… 
National Institutes of Health

Related topics

Related topics

9 relations

Narrower (3)

AzoptSimbrinzabrinzolamide 10 MG/ML Ophthalmic Suspension [Azopt]

Broader (3)

Carbonic Anhydrase InhibitorsSulfonamidesThiazines
Drug AllergyGlaucoma, Open-AngleKidney Failure

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic cyanobacterium Nostoc commune.
2011
2011
Asymmetry of 24-hour intraocular pressure reduction by topical ocular hypotensive medications in fellow eyes.
2009
2009
Carbonic anhydrase inhibitors. Inhibition studies of a coral secretory isoform by sulfonamides.
2008
2008
Effects of topical administration of 1% brinzolamide on intraocular pressure in clinically normal horses.
REASONS FOR PERFORMING STUDY Only few drugs with limited efficacy are available for topical treatment of equine glaucoma… 
2007
2007
Cellular Cytotoxicity of Antiglaucoma Drugs in Cultured Corneal Endothelial Cells
2006
2006
The in vitro effects of some pesticides on carbonic anhydrase activity of Oncorhynchus mykiss and Cyprinus carpio carpio fish.
2006
2006
Effects of Antiglaucoma Drugs on Calcium Mobility in Cultured Corneal Endothelial Cells
2003
2003
Effects of brinzolamide on aqueous humor dynamics in monkeys and rabbits.
This study examines the mechanisms by which brinzolamide reduces intraocular pressure (IOP) in healthy rabbits and in monkeys… 
2003
2003
Effects of topical administration of 1% brinzolamide on normal cat eyes.
OBJECTIVE To evaluate the effect of short-term daily topical administration of 1% brinzolamide on the intraocular pressure (IOP… 
Highly Cited
1999
Highly Cited
1999
Cost considerations of medical therapy for glaucoma.
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