The pathophysiology and treatment of glaucoma: a review.
- R. Weinreb, T. Aung, F. Medeiros
- MedicineJAMA
- 14 May 2014
Primary care physicians can play an important role in the diagnosis of glaucoma by referring patients with positive family history or with suspicious optic nerve head findings for complete ophthalmologic examination and can improve treatment outcomes by reinforcing the importance of medication adherence and persistence.
Primary open-angle glaucoma
- R. Weinreb, C. Leung, K. Martin
- MedicineNature Reviews Disease Primers
- 22 September 2016
Primary open-angle glaucoma (POAG) is the most common type and management of POAG includes topical drug therapies and surgery to reduce IOP, although new therapies targeting neuroprotection of RGCs and axonal regeneration are under development.
Prevalence of Ocular Surface Disease in Glaucoma Patients
- E. W. Leung, F. Medeiros, R. Weinreb
- MedicineJournal of glaucoma
- 1 August 2008
The coexistence of OSD and the use of BAK-containing medications may impact vision-related quality of life in this patient population of glaucoma patients.
Evaluation of the Influence of Corneal Biomechanical Properties on Intraocular Pressure Measurements Using the Ocular Response Analyzer
- F. Medeiros, R. Weinreb
- MedicineJournal of glaucoma
- 1 October 2006
ORA IOPCC measurements seem to provide an estimate of IOP that is less influenced by corneal properties than those provided by GAT, and these measurements were not associated with any of the ocular variables.
Histopathologic validation of Fourier-ellipsometry measurements of retinal nerve fiber layer thickness.
- R. Weinreb, A. Dreher, A. Coleman, H. Quigley, B. Shaw, K. Reiter
- MedicineA M A Archives of Ophthalmology
- 1 April 1990
Quantitating retinal nerve fiber layer thickness may enhance discrimination between glaucomatous and normal eyes earlier than is currently available by anatomic and functional approaches.
Evaluation of retinal nerve fiber layer, optic nerve head, and macular thickness measurements for glaucoma detection using optical coherence tomography.
- F. Medeiros, L. Zangwill, C. Bowd, R. Vessani, R. Susanna, R. Weinreb
- MedicineAmerican journal of ophthalmology-glaucoma
- 2005
Twenty-four-hour intraocular pressure pattern associated with early glaucomatous changes.
- John H. K. Liu, Xiaoyan Zhang, D. Kripke, R. Weinreb
- MedicineInvestigative Ophthalmology and Visual Science
- 1 April 2003
The diurnal IOP is higher, the diurnal-to-nocturnal change of habitual Iop is less, and the posture-independent IOP pattern around normal awakening time is different in eyes with early glaucomatous changes.
Common Variants at 9p21 and 8q22 Are Associated with Increased Susceptibility to Optic Nerve Degeneration in Glaucoma
It is suggested that neuro-protective therapies targeting TGF-beta signaling could be effective for multiple forms of glaucoma, and genomic pathway analysis showed an association between the T GF-beta pathway and NPG.
Comparison of macular thickness measurements between time domain and spectral domain optical coherence tomography.
Although both time domain and spectral domain OCTs are reliable for macular thickness measurements, spectraldomain OCT has better measurement repeatability compared with time domain OCT.
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