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brequinar
Known as:
6-Fluoro-2-(2'-fluoro[1,1'-biphenyl]-4-yl)-3-methyl-4-quinolinecarboxylic Acid
, 6-fluoro-2-(2'-fluoro-1,1'-biphenyl-4-yl)-3-methyl-4-quinolinecarboxylic acid
, Bipenquinate
A synthetic quinolinecarboxylic acid analogue with antineoplastic properties. Brequinar inhibits the enzyme dihydroorotate dehydrogenase, thereby…
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National Institutes of Health
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Related topics
Related topics
8 relations
Broader (4)
Antineoplastic Agents
Biphenyl Compounds
Enzyme Inhibitors
Immunosuppressive Agents
Narrower (2)
DuP 785
NSC 368390
NCIt Antineoplastic Agent Terminology
brequinar sodium
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
PREPARATION HAVING IMPROVED THERAPEUTIC BREADTH COMPRISING NUCLEOTIDE SYNTHESIS INHIBITORS CROSS-REFERENCE TO RELATED APPLICATIONS
2017
Corpus ID: 54912504
A preparation comprising a compound which essentially prevents the enterohepatic circulation of nucleotide Synthe sis inhibitors…
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2010
2010
, Resistance to Brequinar in Cell Culture Characterization of Dengue Virus
Min Qing
,
Gang Zou
,
+4 authors
P. Shi
2010
Corpus ID: 207761560
2004
2004
Rat dihydroorotate dehydrogenase (DHOD)in complex with brequinar
M. Hansen
,
J. L. Nours
,
+4 authors
S. Larsen
2004
Corpus ID: 91920852
1998
1998
FLOW CYTOMETRIC (FCM) ANALYSIS OF THE MOLECULAR MECHANISMS OF IMMUNOSUPPRESSIVE ACTION OF THE ACTIVE METABOLITE OF LEFLUNOMIDE AND ITS MALONONITRILAMIDE (MNA) ANALOGS IN A NOVEL WHOLE BLOOD ASSAY
S. Slauson
,
H. Silva
,
Steven W. Sherwood
,
Randall Ellis Morris
1998
Corpus ID: 25473807
1997
1997
Revisªo/AtualizaÁªo em Transplante Renal: Novos agentes imunossupressores
Mário Abbud Filho
,
Horácio José Ramalho
1997
Corpus ID: 74740589
A imunossupressao clinica foi iniciada no comeco dos anos 50 com o uso de glicocorticoides associados a azatioprina e/ou…
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1997
1997
Immunologie in de medische praktijk. VI. Nieuwe immunosuppressieve geneesmiddelen
M. BergetenR.J.
,
P. T. A. Schellekens
1997
Corpus ID: 58112107
Immunosuppressive drugs are agents capable of modulating at least one type of immune response in vivo at doses with tolerable…
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Review
1995
Review
1995
Pharmacologic immunosuppression: Cure or curse?
A. Wahrenberger
Critical Care Nursing Quarterly
1995
Corpus ID: 34582419
With the advent of cyclosporine in the 1980s, transplantation has become the treatment of choice for many end-stage organ…
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1994
1994
Immunosuppressive Therapie nach Lebertransplantation
J. Langrehr
,
R. Lohmann
,
+9 authors
P. Neuhaus
1994
Corpus ID: 72686784
Mit der Entwicklung mehrerer neuer immunosuppressiver Substanzen in der letzten Zeit ist die medikamentose Therapie nach…
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1994
1994
Immunoassay reagents and methods for the detection of brequinar and analogs
ガルブレイス，ウイリアム
,
サイモン，ポール・ムーア
,
バツト，ダグラス・ガイ
1994
Corpus ID: 103393499
(57) Abstract: The present invention is an antibody specific to quinolinecarboxylic acid for example brequinar, the joint as a…
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1990
1990
Effects of brequinar and ciprofloxacin on de novo nucleotide biosynthesis in mouse L1210 leukemia.
S. D. Lyons
,
R. Christopherson
Biochemistry International
1990
Corpus ID: 20037060
Exposure of mouse L1210 leukemia cells to 25 microM brequinar for 4 h results in large accumulations of N-carbamyl-L-aspartate…
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