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NSC 368390
Known as:
NSC-368390
National Institutes of Health
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1 relation
Broader (1)
brequinar
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2006
2006
Phase I and Pharmacokinetic Study of Brequinar Sodium (NSC 368390)1
D. Noe
,
E. Rowinsky
,
+8 authors
R. Donehower
2006
Corpus ID: 13096972
Brequinar sodium is a quinoline carboxylic acid derivative that has shown antitumor activity in a number of in vivomurine and…
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2006
2006
Phase I Clinical and Pharmacokinetic Trial of Brequinar Sodium ( DUP 785 ; NSC 368390 ) 1
C. Arteaga
,
T. Brown
,
+8 authors
G. Weiss
2006
Corpus ID: 15786767
Brequinar sodium is a 4-quinolinecarboxylic acid analogue that inhibits dihydroorotate dehydrogenase and subsequent tic novo…
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2006
2006
Biosynthesis Pyrimidine Nucleotide de Novo ( NSC 368390 ) : Inhibition of-biphenyl-4-yl )-3-methyl-4-quinolinecarboxylic Acid Sodium Salt ′-fluoro-1 , 1 ′ 6-Fluoro-2-( 2 Mechanism of Action of the…
S. Chen
,
R. L. Ruben
,
D. Dexter
2006
Corpus ID: 2473955
Exposure of cultured clone A human colon tumor cells to 25 to 75 MM of NSC 368390 |6-fluoro-2-(2'-fluoro-l,l'-biphenyl-4-yl)-3…
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1988
1988
113 THE RELATIONSHIP BETWEEN DIHYDROOROTIC ACID DEHYDROGENASE AND IN VITRO AND IN VIVO CYTOSTATIC EFFECTS OF BREQUINAR (DUF-785; NSC 368390)
G. Peters
,
E. Laurensse
,
E. Kant
,
J. C. Nadal
,
H. Pinedo
Pediatric Research
1988
Corpus ID: 45520176
DUP-785 (Brequinar sodium) is a novel potent inhibitor of the pyrimidine de novo enzyme dihydroorotic acid dehydrogenase (DHO-DH…
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1988
1988
Essai clinique phase i du dup 785 (nsc 368390) conduit a l'institut gustave roussy sur le schema d'une courte administration intra-veineuse 5 jours consecutifs (protocole 002c1) : analyse…
M. Forni
1988
Corpus ID: 190298438