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DuP 785

Known as: DUP-785, DUP785 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

brequinarbrequinar sodium

Papers overview

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2006
2006
Phase I Clinical and Pharmacokinetic Trial of Brequinar Sodium ( DUP 785 ; NSC 368390 ) 1
Brequinar sodium is a 4-quinolinecarboxylic acid analogue that inhibits dihydroorotate dehydrogenase and subsequent tic novo… 
2004
2004
Application of a new preclinical drug screening system for cancer of the large bowel
SummaryWe report a prospective evaluation of three human, continuous colorectal cancer cell lines and a new semiautomated… 
1993
1993
Environmental/Occupational Medicine Awards
Brequinar sodium (DUP-785; Brequinar) is a potent inhibitor of the pyrimidine de novo enzyme dihydroorotate dehydrogenase (DHO-DH… 
1990
1990
Antitumor activity of brequinar sodium (Dup-785) against human head and neck squamous cell carcinoma xenografts.
1989
1989
Cellular pharmacology of DUP-785, a new anticancer agent.
DUP-785, a new inhibitor of dihydroorotate dehydrogenase, is currently undergoing clinical evaluation for anticancer activity. We… 
1989
1989
The relationship between dihydroorotic acid dehydrogenase and in vitro and in vivo cytostatic effects of brequinar sodium (DUP-785; NSC 368390).
1988
1988
113 THE RELATIONSHIP BETWEEN DIHYDROOROTIC ACID DEHYDROGENASE AND IN VITRO AND IN VIVO CYTOSTATIC EFFECTS OF BREQUINAR (DUF-785; NSC 368390)
DUP-785 (Brequinar sodium) is a novel potent inhibitor of the pyrimidine de novo enzyme dihydroorotic acid dehydrogenase (DHO-DH… 
1987
1987
[Progress in experimental chemotherapy of colorectal cancer].
The aim of the present study was a prospective evaluation of the predictive value of a new system as a primary screen for… 
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