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aranidipine

Known as: methyl 2-oxopropyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Dihydropyridines

Narrower (1)

MPC 1304

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Quantitative structure-interaction relationship analysis of 1,4-dihydropyridine drugs in concomitant administration with grapefruit juice.
Quantitative structure-interaction relationship (QSIR) analyses of 1,4-dihydropyridine drugs were performed on grapefruit juice… 
2009
2009
Five different profiles of dihydropyridines in blocking T-type Ca(2+) channel subtypes (Ca(v)3.1 (alpha(1G)), Ca(v)3.2 (alpha(1H)), and Ca(v)3.3 (alpha(1I))) expressed in Xenopus oocytes.
2006
2006
Determination of aranidipine and its active metabolite in human plasma by liquid chromatography/negative electrospray ionization tandem mass spectrometry.
A simple, sensitive and rapid high-performance liquid chromatography/negative electrospray ionization tandem mass spectrometry… 
2000
2000
Inhibition of T-Type and L-Type Ca2+ Currents by Aranidipine, a Novel Dihydropyridine Ca2+ Antagonist
The effects of aranidipine, a novel dihydropyridine Ca2+ channel antagonist, on membrane currents in guinea pig ventricular… 
2000
2000
Distinct action of aranidipine and its active metabolite on renal arterioles, with special reference to renal protection.
Aranidipine, a newly developed calcium antagonist, possesses unique pharmacologic characteristics in that its metabolite (M-1… 
1999
1999
Newer calcium channel antagonists and the treatment of hypertension.
Calcium channel antagonists have become popular medications for the management of hypertension. These agents belong to the… 
1998
1998
Renal effects of the calcium channel blocker aranidipine and its active metabolite in anesthetized dogs and conscious spontaneously hypertensive rats.
The purpose of this study was to investigate the renal effects of aranidipine, a novel calcium channel blocker of the… 
1997
1997
Effects of aranidipine, a novel calcium channel blocker, on mechanical responses of the isolated rat portal vein: comparison with typical calcium channel blockers and potassium channel openers.
We investigated the effects of aranidipine, a dihydropyridine-type Ca2+ channel blocker, on contractile responses to KCl and… 
1996
1996
Contribution of aranidipine metabolites with slow binding kinetics to the vasodilating activity of aranidipine
Abstract Aranidipine, a novel dihydropyridine derivative, gives rise to two active metabolites, M-1(α) and M-1(β), which exhibit… 
Review
1996
Review
1996
Aranidipine (MPC-1304), a New Dihydropyridine Calcium Antagonist: A Review of Its Antihypertensive Action
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