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Dopaminergic agonists impair latent learning in mice: possible modulation by noradrenergic function.
The effects of the dopamine agonists apomorphine, GBR-12909, nomifensine and methamphetamine on latent learning were investigated using a one-trial, water-finding task in mice. Mice without waterExpand
Effects of haloperidol, sulpiride and SCH 23390 on passive avoidance learning in mice.
The main purpose of the present study was to examine the effect of dopamine blockers on memory processes by means of a one-trial passive avoidance (PA) task with ddY mice. Haloperidol (0.025-0.4Expand
Lifespan-Extending Effects of Royal Jelly and Its Related Substances on the Nematode Caenorhabditis elegans
Background One of the most important challenges in the study of aging is to discover compounds with longevity-promoting activities and to unravel their underlying mechanisms. Royal jelly (RJ) hasExpand
The effects of Brazilian green propolis that contains flavonols against mutant copper-zinc superoxide dismutase-mediated toxicity
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the selective and progressive loss of motor neurons. The purpose of this study was to clarify effects ofExpand
10-Hydroxy-2-decenoic Acid, the Major Lipid Component of Royal Jelly, Extends the Lifespan of Caenorhabditis elegans through Dietary Restriction and Target of Rapamycin Signaling
Royal jelly (RJ) produced by honeybees has been reported to possess diverse health-beneficial properties and has been implicated to have a function in longevity across diverse species as well asExpand
Artepillin C, a Major Ingredient of Brazilian Propolis, Induces a Pungent Taste by Activating TRPA1 Channels
Brazilian green propolis is a popular health supplement because of its various biological properties. The ethanol extract of Brazilian green propolis (EEBP) is characteristic for its herb-like smellExpand
Propolis cinnamic acid derivatives induce apoptosis through both extrinsic and intrinsic apoptosis signaling pathways and modulate of miRNA expression.
Propolis cinnamic acid derivatives have a number of biological activities including anti-oxidant and anti-cancer ones. In this study, we aimed to elucidate the mechanism of the anti-cancer activityExpand
Autophagy inhibition enhances anticancer efficacy of artepillin C, a cinnamic acid derivative in Brazilian green propolis.
Propolis, a resinous substance produced by honeybees, possesses various biological actions including anticancer activity towards tumor cells. Recently, the ethanol extract of Brazilian green propolisExpand
Agarwood (Aquilaria Crassna) Extracts Decrease High-protein High-fat Diet-induced Intestinal Putrefaction Toxins in Mice
Agarwood (Aquilaria spp.) is famous for its aromatic resin, but its leaves are also prized as a healthy tea in South East Asia. Previously, we reported that agarwood extract (Aquilaria sinensis andExpand
Effects of benzodiazepines on passive avoidance response and latent learning in mice: relationship to benzodiazepine receptors and the cholinergic neuronal system.
The effects of benzodiazepines on learning and memory were investigated, using passive avoidance and latent learning tasks, with particular attention being paid to the possible involvement ofExpand