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alitretinoin

Known as: Alitretinoína, (2e,4e,6Z,8e)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid, 9-cis-RA 
An orally- and topically-active naturally-occurring retinoic acid with antineoplastic, chemopreventive, teratogenic, and embryotoxic activities… Expand
National Institutes of Health

Papers overview

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Highly Cited
2000
Highly Cited
2000
Tangier disease, a condition characterized by low levels of high density lipoprotein and cholesterol accumulation in macrophages… Expand
Review
1997
Review
1997
BACKGROUND Hereditary pancreatitis is an autosomal-dominant disease, with a variable expression and an estimated penetrance of 80… Expand
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Highly Cited
1996
Highly Cited
1996
Increased activity of lipoprotein lipase (LPL) may explain the hypotriglyceridemic effects of fibrates, thiazolidinediones and… Expand
Highly Cited
1995
Highly Cited
1995
The crystal structure of the human retinoid-X receptor RXR-α ligand-binding domain reveals a previously undiscovered fold of an… Expand
Highly Cited
1995
Highly Cited
1995
We have identified a new retinoid response pathway through which 9-cis retinoic acid (9cRA) activates transcription in the… Expand
Highly Cited
1994
Highly Cited
1994
Previously, we have isolated and characterized an enhancer from the 5'-flanking region of the adipocyte P2 (aP2) gene that… Expand
Review
1992
Review
1992
PEROXISOMES are cytoplasmic organelles which are important in mammals in modulation of lipid homeostasis, including the… Expand
Highly Cited
1992
Highly Cited
1992
All-trans retinoic acid (RA) has previously been shown to modulate the transcriptional properties of the retinoic acid receptor… Expand
Highly Cited
1992
Highly Cited
1992
VITAMIN A (retinol) and its natural derivatives are required for many physiological processes1–3. The activity of retinoids is… Expand
Highly Cited
1992
Highly Cited
1992
An understanding of the differences and similarities of the retinoid X receptor (RXR) and retinoic acid receptor (RAR) systems… Expand
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