X-Box Binding Protein 1, Human

Known as: Tax-Responsive Element-Binding Protein 5, TREB5 protein, human, tax-responsive element-binding protein 5, human 
X-box binding protein 1 (261 aa, ~29 kDa) is encoded by the human XBP1 gene. This protein is a bZIP transcription factor that is involved in both the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2000-2018
051020002018

Papers overview

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Highly Cited
2009
Highly Cited
2009
Mutations in superoxide dismutase-1 (SOD1) cause familial amyotrophic lateral sclerosis (fALS). Recent evidence implicates… (More)
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2009
2009
Statins are compounds prescribed to lower blood cholesterol in millions of patients worldwide. They act by inhibiting HMG-CoA… (More)
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2009
2009
Endoplasmic reticulum (ER) stress has been extensively described in many protein misfolding disorders including amyotrophic… (More)
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2008
2008
The transcription factor X-box-binding protein-1 (XBP-1) plays an essential role in activating the unfolded protein response in… (More)
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2008
2008
The optimization of production processes for therapeutic antibodies is a continuing challenge in pharmaceutical biotechnology… (More)
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2007
2007
BACKGROUND Human X-box binding protein 1 (XBP-1) is a transcription factor essential for hepatocyte growth, as well as for plasma… (More)
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2007
2007
Brain ischemia and reperfusion (I/R) induce neuronal intracellular stress responses, including the heat-shock response (HSR) and… (More)
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Highly Cited
2005
Highly Cited
2005
The unfolded protein response (UPR) is an adaptive signaling pathway utilized to sense and alleviate the stress of protein… (More)
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Highly Cited
2003
Highly Cited
2003
The transcription factor X-box binding protein 1 (XBP-1) is essential for the differentiation of plasma cells and the unfolded… (More)
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Highly Cited
2000
Highly Cited
2000
XBP-1 is a CREB/ATF family transcription factor highly expressed in hepatocellular carcinomas. Here we report that XBP-1 is… (More)
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