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X-Box Binding Protein 1

Known as: Tax Responsive Element Binding Protein 5, Tax-Responsive Element-Binding Protein 5, TREB-5 Protein 
A basic leucine zipper transcription factor that regulates expression of MHC CLASS II GENES through its binding to a conserved X-box DNA sequence in… 
National Institutes of Health

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In BloodProcess of secretionXBP1 geneagonists

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X-Box Binding Protein 1, Human

Papers overview

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Highly Cited
2016
Highly Cited
2016
Ammonia exposure induces oxidative stress, endoplasmic reticulum stress and apoptosis in hepatopancreas of pacific white shrimp (Litopenaeus vannamei).
2015
2015
Melatonin inhibits tunicamycin-induced endoplasmic reticulum stress and insulin resistance in skeletal muscle cells.
2015
2015
Insertion of a xylanase in xylose binding protein results in a xylose-stimulated xylanase
BackgroundProduct inhibition can reduce catalytic performance of enzymes used for biofuel production. Different mechanisms can… 
Highly Cited
2014
Highly Cited
2014
Interplay Between the Oxidoreductase PDIA6 and microRNA-322 Controls the Response to Disrupted Endoplasmic Reticulum Calcium Homeostasis
Depletion of Ca2+ in the endoplasmic reticulum favors activation of a stress response involving IRE1α. Responding the Right Way… 
Review
2010
Review
2010
Emerging roles for XBP1, a sUPeR transcription factor.
X-box binding protein 1 (XBP1) is a unique basic region leucine zipper (bZIP) transcription factor whose active form is generated… 
Highly Cited
2010
Highly Cited
2010
XBP1s levels are implicated in the biology and outcome of myeloma mediating different clinical outcomes to thalidomide-based treatments.
Immunoglobulin production by myeloma plasma cells depends on the unfolded protein response for protein production and folding… 
Highly Cited
2009
Highly Cited
2009
XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development
The unfolded protein response (UPR) is a stress response pathway that is driven by the increased load of unfolded proteins in the… 
Highly Cited
2007
Highly Cited
2007
West Nile Virus Infection Activates the Unfolded Protein Response, Leading to CHOP Induction and Apoptosis
ABSTRACT West Nile virus (WNV)-mediated neuronal death is a hallmark of WNV meningitis and encephalitis. However, the mechanisms… 
2004
2004
XBP-1 increases ERalpha transcriptional activity through regulation of large-scale chromatin unfolding.
Highly Cited
1996
Highly Cited
1996
Transcription factor B cell lineage-specific activator protein regulates the gene for human X-box binding protein 1
The transcription factor human X-box binding protein 1 (hXBP-1) is a basic region-leucine zipper protein implicated in the… 
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