XBP1 gene

Known as: XBP1, X BOX-BINDING PROTEIN 1, X-Box Binding Protein 1 Gene 
This gene is involved in the transcription of major histocompatibility complex class II genes and the response to endoplasmic reticulum stress.
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Sensors of pathogens, such as Toll-like receptors (TLRs), detect microbes to activate transcriptional programs that orchestrate… (More)
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Highly Cited
2008
Highly Cited
2008
Inflammatory bowel disease (IBD) has been attributed to aberrant mucosal immunity to the intestinal microbiota. The transcription… (More)
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Highly Cited
2008
Highly Cited
2008
Dietary carbohydrates regulate hepatic lipogenesis by controlling the expression of critical enzymes in glycolytic and lipogenic… (More)
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Highly Cited
2007
Highly Cited
2007
Metazoans express three unfolded protein response transducers (IRE1, PERK, and ATF6) ubiquitously to cope with endoplasmic… (More)
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Highly Cited
2007
Highly Cited
2007
Using genome-wide approaches, we have elucidated the regulatory circuitry governed by the XBP1 transcription factor, a key… (More)
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Highly Cited
2006
Highly Cited
2006
Upon the accumulation of unfolded proteins in the mammalian endoplasmic reticulum (ER), X-box binding protein 1 (XBP1… (More)
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Highly Cited
2004
Highly Cited
2004
The differentiation of B cells into immunoglobulin-secreting plasma cells is controlled by two transcription factors, Blimp-1 and… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND/AIMS We identified the glucose-regulated protein (grp) 78 as a transformation-associated gene in hepatocellular… (More)
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Highly Cited
2002
Highly Cited
2002
All eukaryotic cells respond to the accumulation of unfolded proteins in the endoplasmic reticulum (ER) by signaling an adaptive… (More)
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Highly Cited
2001
Highly Cited
2001
In yeast, the transmembrane protein kinase/endoribonuclease Ire1p activated by endoplasmic reticulum stress cleaves HAC1 mRNA… (More)
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