Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 217,273,901 papers from all fields of science
Search
Sign In
Create Free Account
Valproic Acid
Known as:
2 Propylpentanoic Acid
, Valproic Acid [Chemical/Ingredient]
, DIVALPROEX
Expand
A synthetic derivative of propylpentanoic acid with antiepileptic properties and potential antineoplastic and antiangiogenesis activities. In…
Expand
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
44 relations
Narrower (23)
1,4-butanediol divalproate
2-fluoro-2-propyl-4-pentenoic acid
3-aminopentanoic acid
3-hydroxymethylphenytoin valproic acid ester
Expand
Antiepileptic Agents
Antimanic Agents
Bipolar Disorder
Childhood Absence Epilepsy
Expand
Broader (2)
Enzyme Inhibitors
GABA Agents
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Omega-3 fatty acids and cardiovascular disease: effects on risk factors, molecular pathways, and clinical events.
D. Mozaffarian
,
Jason H. Y. Wu
Journal of the American College of Cardiology
2011
Corpus ID: 30198700
Review
2010
Review
2010
Valproic acid monotherapy in pregnancy and major congenital malformations.
J. Jentink
,
M. Loane
,
+4 authors
L. de Jong-van den Berg
New England Journal of Medicine
2010
Corpus ID: 15514140
BACKGROUND The use of valproic acid in the first trimester of pregnancy is associated with an increased risk of spina bifida, but…
Expand
Review
2010
Review
2010
Molecular and Therapeutic Potential and Toxicity of Valproic Acid
Sébastien Chateauvieux
,
F. Morceau
,
M. Dicato
,
M. Diederich
Journal of Biomedicine and Biotechnology
2010
Corpus ID: 15198793
Valproic acid (VPA), a branched short-chain fatty acid, is widely used as an antiepileptic drug and a mood stabilizer…
Expand
Review
2008
Review
2008
Obesity
G. Bray
,
J. Wilson
Annals of Internal Medicine
2008
Corpus ID: 34210059
Editor's Note: This issue of In the Clinic has been updated. More than 30% of U.S. adults are obese (1). Generally defined as a…
Expand
Highly Cited
2007
Highly Cited
2007
Molecular Cancer
Ken Sasai
,
Tsuyoshi Akagi
,
E. Aoyanagi
,
Kouichi Tabu
,
Sadao Kaneko
,
Shinya Tanaka
2007
Corpus ID: 9461909
Open Access Research O 6-methylguanine-DNA methyltransferase is downregulated in transformed astrocyte cells: implications for…
Expand
Highly Cited
2005
Highly Cited
2005
Behavioral Alterations in Rats Prenatally Exposed to Valproic Acid: Animal Model of Autism
T. Schneider
,
R. Przewłocki
Neuropsychopharmacology
2005
Corpus ID: 11537160
Autism is a severe behavioral disorder characterized by pervasive impairments in social interactions, deficits in verbal and…
Expand
Highly Cited
2003
Highly Cited
2003
The histone deacetylase inhibitor valproic acid selectively induces proteasomal degradation of HDAC2
O. Krämer
,
P. Zhu
,
+8 authors
M. Göttlicher
EMBO Journal
2003
Corpus ID: 28759160
Histone‐modifying enzymes play essential roles in physiological and aberrant gene regulation. Since histone deacetylases (HDACs…
Expand
Highly Cited
2002
Highly Cited
2002
Age and gender differences in objectively measured physical activity in youth.
S. Trost
,
R. Pate
,
+4 authors
J. Sirard
Medicine & Science in Sports & Exercise
2002
Corpus ID: 34460687
PURPOSE The purpose of this study was to evaluate age and gender differences in objectively measured physical activity (PA) in a…
Expand
Highly Cited
2001
Highly Cited
2001
Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells
M. Göttlicher
,
S. Minucci
,
+8 authors
T. Heinzel
EMBO Journal
2001
Corpus ID: 26937077
Histone deacetylases (HDACs) play important roles in transcriptional regulation and pathogenesis of cancer. Thus, HDAC inhibitors…
Expand
Highly Cited
2001
Highly Cited
2001
Histone Deacetylase Is a Direct Target of Valproic Acid, a Potent Anticonvulsant, Mood Stabilizer, and Teratogen*
C. Phiel
,
Fang Zhang
,
E. Huang
,
M. Guenther
,
M. Lazar
,
P. S. Klein
Journal of Biological Chemistry
2001
Corpus ID: 35216563
Valproic acid is widely used to treat epilepsy and bipolar disorder and is also a potent teratogen, but its mechanisms of action…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
(opens in a new tab)
,
Terms of Service
(opens in a new tab)
, and
Dataset License
(opens in a new tab)
ACCEPT & CONTINUE