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We reviewed available evidence for cardiovascular effects of n-3 polyunsaturated fatty acid (PUFA) consumption, focusing on long… Expand BACKGROUND
The use of valproic acid in the first trimester of pregnancy is associated with an increased risk of spina bifida, but… Expand BACKGROUND
Childhood absence epilepsy, the most common pediatric epilepsy syndrome, is usually treated with ethosuximide… Expand Editor's Note: This issue of In the Clinic has been updated. More than 30% of U.S. adults are obese (1). Generally defined as a… Expand Autism is a severe behavioral disorder characterized by pervasive impairments in social interactions, deficits in verbal and… Expand PURPOSE
The purpose of this study was to evaluate age and gender differences in objectively measured physical activity (PA) in a… Expand Histone deacetylases (HDACs) play important roles in transcriptional regulation and pathogenesis of cancer. Thus, HDAC inhibitors… Expand Valproic acid is widely used to treat epilepsy and bipolar disorder and is also a potent teratogen, but its mechanisms of action… Expand Using confocal microscopy, onset of the mitochondrial permeability transition (MPT) in individual mitochondria within living… Expand We reviewed all US cases of fatal hepatotoxicity coincident with valproate anticonvulsant therapy that were reported between 1978… Expand