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Valproic Acid

Known as: 2 Propylpentanoic Acid, Valproic Acid [Chemical/Ingredient], DIVALPROEX 
A synthetic derivative of propylpentanoic acid with antiepileptic properties and potential antineoplastic and antiangiogenesis activities. In… Expand
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Policy Points: Our study indicates that there are opportunities for cost savings in generic drug markets in Europe and the United… Expand
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Review
2010
Review
2010
BACKGROUND The use of valproic acid in the first trimester of pregnancy is associated with an increased risk of spina bifida, but… Expand
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Highly Cited
2006
Highly Cited
2006
We conducted a phase 1/2 study of the combination of 5-aza-2'-deoxycytidine (decitabine) and the histone deacetylase inhibitor… Expand
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Highly Cited
2005
Highly Cited
2005
Autism is a severe behavioral disorder characterized by pervasive impairments in social interactions, deficits in verbal and… Expand
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Highly Cited
2003
Highly Cited
2003
Histone‐modifying enzymes play essential roles in physiological and aberrant gene regulation. Since histone deacetylases (HDACs… Expand
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Highly Cited
2002
Highly Cited
2002
PURPOSE The purpose of this study was to evaluate age and gender differences in objectively measured physical activity (PA) in a… Expand
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Highly Cited
2001
Highly Cited
2001
Histone deacetylases (HDACs) play important roles in transcriptional regulation and pathogenesis of cancer. Thus, HDAC inhibitors… Expand
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Highly Cited
2001
Highly Cited
2001
Valproic acid is widely used to treat epilepsy and bipolar disorder and is also a potent teratogen, but its mechanisms of action… Expand
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Highly Cited
1999
Highly Cited
1999
Differential Power Analysis, first introduced by Kocher et al. in [14], is a powerful technique allowing to recover secret smart… Expand
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Review
1998
Review
1998
Using confocal microscopy, onset of the mitochondrial permeability transition (MPT) in individual mitochondria within living… Expand
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